Targeted pancreatic cancer therapy using 4-farnesyloxycoumarin conjugated nanocrystalline cellulose and Chitosan nanoparticles

Targeted pancreatic cancer therapy using 4-farnesyloxycoumarin conjugated nanocrystalline cellulose and Chitosan nanoparticles

Abstract This study investigates the effects of 4-farnesyloxycoumarin (4-FOC)-conjugated NCC/CTAB/CS nanoparticles (NPs) on PANC-1 pancreatic cancer cells, highlighting their cytotoxicity and antioxidant properties. Dynamic light scattering (DLS) analysis revealed a Z-average particle size of 275.68...

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Bibliographic Details
Main Authors: Fariba Karoonkiani, Masoud Homayouni Tabrizi, Mohammad Taghi Goodarzi, Alireza Jalali
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
4-Farnesyl oxy coumarin
Nanoparticles
Pancreatic neoplasms
Antioxidants
Cytotoxicity
Apoptosis
Online Access:https://doi.org/10.1038/s41598-025-02344-w
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