CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN
Objectives. To conduct a scoping review of the scientific literature summarizing current knowledge regarding gender-related differences in conventional and the impact of non-conventional risk factors for peripheral arterial disease (PAD) in women. Methods. A comprehensive literature search was pe...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Association of Surgeons of the Republic of Moldova
2025-03-01
|
| Series: | Arta Medica |
| Subjects: | |
| Online Access: | http://www.artamedica.md/index.php/artamedica/article/view/379 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849248303944826880 |
|---|---|
| author | Igor Spinei Dragoș-Alexandru Lubaș Dumitru Casian |
| author_facet | Igor Spinei Dragoș-Alexandru Lubaș Dumitru Casian |
| author_sort | Igor Spinei |
| collection | DOAJ |
| description |
Objectives. To conduct a scoping review of the scientific literature summarizing current knowledge regarding gender-related differences in conventional and the impact of non-conventional risk factors for peripheral arterial disease (PAD) in women.
Methods. A comprehensive literature search was performed across PubMed, MEDLINE, SCOPUS and Google Scholar databases examining the risk factors for PAD. After initial identification of the most relevant articles, forward and backward citation tracking was performed for selection of additional publications. Finally, a total of 49 publications (43 original articles, 2 systematic reviews and 2 clinical practice guidelines) were included and analysed.
Results. Conventional factors for the development and progression of PAD have several sex-specific features in women: more significant impact of smoking and diabetes, less effective correction of dyslipidemia and hypertension, frequent association with obesity and osteoporosis. Furthermore, current evidence highlights the importance of non-conventional risk factors for PAD in females: sex-hormones disbalance, reproductive history and adverse obstetric events.
Conclusions. There are numerous gender-related peculiarities in the natural evolution of PAD in female patients which may influence the clinical presentation, diagnosis and outcomes of medical and interventional treatment. Further studies are required for a better understanding of sex-related vulnerability mechanisms and elaboration of individualized management.
|
| format | Article |
| id | doaj-art-7da083e70bba4beaaf041dfb100d95e9 |
| institution | Kabale University |
| issn | 1810-1852 1810-1879 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Association of Surgeons of the Republic of Moldova |
| record_format | Article |
| series | Arta Medica |
| spelling | doaj-art-7da083e70bba4beaaf041dfb100d95e92025-08-20T03:57:55ZengAssociation of Surgeons of the Republic of MoldovaArta Medica1810-18521810-18792025-03-0194110.5281/zenodo.15880359CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMENIgor Spinei0Dragoș-Alexandru Lubaș1Dumitru Casian2“Nicolae Testemițanu” State University of Medicine and Pharmacy, Chișinău, Republic of Moldova“Nicolae Testemițanu” State University of Medicine and Pharmacy, Chișinău, Republic of Moldova“Nicolae Testemițanu” State University of Medicine and Pharmacy, Chișinău, Republic of Moldova Objectives. To conduct a scoping review of the scientific literature summarizing current knowledge regarding gender-related differences in conventional and the impact of non-conventional risk factors for peripheral arterial disease (PAD) in women. Methods. A comprehensive literature search was performed across PubMed, MEDLINE, SCOPUS and Google Scholar databases examining the risk factors for PAD. After initial identification of the most relevant articles, forward and backward citation tracking was performed for selection of additional publications. Finally, a total of 49 publications (43 original articles, 2 systematic reviews and 2 clinical practice guidelines) were included and analysed. Results. Conventional factors for the development and progression of PAD have several sex-specific features in women: more significant impact of smoking and diabetes, less effective correction of dyslipidemia and hypertension, frequent association with obesity and osteoporosis. Furthermore, current evidence highlights the importance of non-conventional risk factors for PAD in females: sex-hormones disbalance, reproductive history and adverse obstetric events. Conclusions. There are numerous gender-related peculiarities in the natural evolution of PAD in female patients which may influence the clinical presentation, diagnosis and outcomes of medical and interventional treatment. Further studies are required for a better understanding of sex-related vulnerability mechanisms and elaboration of individualized management. http://www.artamedica.md/index.php/artamedica/article/view/379peripheral arterial diseaserisk factorsreproductive historywomen |
| spellingShingle | Igor Spinei Dragoș-Alexandru Lubaș Dumitru Casian CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN Arta Medica peripheral arterial disease risk factors reproductive history women |
| title | CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN |
| title_full | CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN |
| title_fullStr | CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN |
| title_full_unstemmed | CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN |
| title_short | CONVENTIONAL AND NON-CONVENTIONAL RISK FACTORS FOR PERIPHERAL ARTERIAL DISEASE IN WOMEN |
| title_sort | conventional and non conventional risk factors for peripheral arterial disease in women |
| topic | peripheral arterial disease risk factors reproductive history women |
| url | http://www.artamedica.md/index.php/artamedica/article/view/379 |
| work_keys_str_mv | AT igorspinei conventionalandnonconventionalriskfactorsforperipheralarterialdiseaseinwomen AT dragosalexandrulubas conventionalandnonconventionalriskfactorsforperipheralarterialdiseaseinwomen AT dumitrucasian conventionalandnonconventionalriskfactorsforperipheralarterialdiseaseinwomen |