Chromium picolinate prevents the development of oxidative-nitrosative stress and restores endogenous H(2)S production in the rat brain under rotenone-induced toxicity

Chromium picolinate prevents the development of oxidative-nitrosative stress and restores endogenous H(2)S production in the rat brain under rotenone-induced toxicity

Energy deficit, mitochondrial dysfunction and oxidative stress induced by rotenone may play a decisive role in the pathogenesis of neurodegenerative disorders. Chromium picolinate has shown neuroprotective activity and efficacy in the treatment of Alzheimer’s disease The effect of chromium picolinat...

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Bibliographic Details
Main Authors: A. O. Mykytenko, I. S. Hrytsenko, A. Y. Semenchuk, M. V. Voroniuk, V. V. Kovpak, O. Y. Akimov, K. S. Neporada
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2025-04-01
Series:The Ukrainian Biochemical Journal
Subjects:
chromium picolinate
no-synthase
oxidative-nitrosative stress
rat brain
rotenon
h2s
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2025/05/Mykytenko_97_2.pdf
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