Multiple mutations in polyketide synthase led to disruption of Psittacofulvin production across diverse parrot species
Abstract Polyketide synthases (PKSs) are crucial multidomain enzymes in diverse natural product biosynthesis. Parrots use a type I PKS to produce a unique pigment called psittacofulvin in their feathers. In domesticated budgerigars and lovebirds, the same amino acid substitution (R644W) within malon...
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| Main Authors: | Shatadru Ghosh Roy, Jindřich Brejcha, Petr Maršík, Anna Bakhrat, Moty Abdu, Roberto Arbore, Pedro Miguel Araújo, Sandra Afonso, Miguel Carneiro, Iris Grossman-Haham, Uri Abdu |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07537-7 |
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