A small library crRNA-enhanced CRISPR-Cas12a system for ultrasensitive point-of-care test of hantavirus M gene
The integration of CRISPR-Cas systems with isothermal nucleic acid amplification (INA) holds transformative potential for point-of-care diagnostics, yet technical challenges such as limited sensitivity, cross-contamination risks, and incompatibility between amplification and detection phases hinder...
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| Main Authors: | Jian Zhou, Xue-mei Ren, Xin Wang, Pu Xu, Zhuo Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Sensing and Bio-Sensing Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214180425000777 |
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