The role of glutathione S-transferase mu 2 in mitigating fatty acid–induced hepatic inflammation in dairy cows

The role of glutathione S-transferase mu 2 in mitigating fatty acid–induced hepatic inflammation in dairy cows

ABSTRACT: Fatty liver is a major metabolic disorder in perinatal dairy cows, characterized by elevated plasma concentrations of nonesterified fatty acids (NEFA) and hepatic inflammation. Glutathione S-transferase mu 2 (GSTM2), a phase II detoxification enzyme, regulates cellular antioxidant and deto...

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Bibliographic Details
Main Authors: Jinxia Li, Chenchen Zhao, Dandan Qi, Fanrong Kong, Menglin Liu, Jie Gao, Enzhu Li, Wenwen Gao, Xiliang Du, Yuxiang Song, Xinwei Li, Haihua Feng, Lin Lei
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Dairy Science
Subjects:
dairy cows
severe fatty liver
GSTM2
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030225000736
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