Family size and cardiovascular disease incidence: a population-level association study

Aim To investigate the population-level association between family size and cardiovascular disease (CVD) incidence, focusing on broad patterns rather than causal mechanisms or individual-level effects.Methods Population level correlations of family size to CVD incidence were analyzed with scatter pl...

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Bibliographic Details
Main Authors: Wenpeng You, Jacob Sevastidis, Maciej Henneberg
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Future Science OA
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Online Access:https://www.tandfonline.com/doi/10.1080/20565623.2025.2495537
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Summary:Aim To investigate the population-level association between family size and cardiovascular disease (CVD) incidence, focusing on broad patterns rather than causal mechanisms or individual-level effects.Methods Population level correlations of family size to CVD incidence were analyzed with scatter plots, simple regression, partial correlation and multivariate regression separately. Aging, economic affluence, obesity and urbanization were incorporated in models as potential confounders.Results Globally, family size negatively correlated to CVD incidence rate. This relationship remained in partial correlation analyses when controlling for confounders. Stepwise multiple regression revealed that family size may be the most significant predictor of CVD incidence.Conclusions Large family size is significantly associated with lower cardiovascular disease (CVD) incidence, potentially due to biological, psychological, and social factors. However, as the data are cross-sectional, this relationship should be interpreted as correlational rather than causal. The association appears more pronounced in developing countries, where contextual factors may amplify its effects.
ISSN:2056-5623