Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report
After early outbreaks in North America in April 2009, the pandemic influenza A (H1N1) virus spread rapidly around the world, and even some patients developed certain severe complications. We reported one case of hemophagocytic lymphohistiocytosis (HLH) induced by severe pandemic influenza A (H1N1) v...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/951910 |
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| author | Xiang-Yan Zhang Xian-Wei Ye Duan-Xing Feng Jing Han Dan Li Cheng Zhang |
| author_facet | Xiang-Yan Zhang Xian-Wei Ye Duan-Xing Feng Jing Han Dan Li Cheng Zhang |
| author_sort | Xiang-Yan Zhang |
| collection | DOAJ |
| description | After early outbreaks in North America in April 2009, the pandemic influenza A (H1N1) virus spread rapidly around the world, and even some patients developed certain severe complications. We reported one case of hemophagocytic lymphohistiocytosis (HLH) induced by severe pandemic influenza A (H1N1) virus infection. A 17-year-old girl had acute onset of fever, dry cough, rhinorrhea, and sore throat Her family members and close friends also had the similar symptoms. Anti-infection treatment with penicillin was given after 8 days of the onset of symptoms in the local hospital, and her chest radiograph showed consolidation of the left lung. Then, she was sent to the People's Hospital of Guizhou Province in China and endotracheal intubation were underwent on the ninth day for acute hypoxic respiratory failure. She was diagnosed with HLH induced by severe pandemic influenza A (H1N1) 2009 virus. Oseltamivir, steroids, immunoglobulin, and plasmapheresis were given immediately after admission. After being treated in the People's Hospital of Guizhou Province for 16 days, she was discharged. This experience shows that HLH may be a life-threatening complication for severe pandemic influenza A (H1N1) 2009 virus infection and responds well to therapy. |
| format | Article |
| id | doaj-art-7d6e5d1f2bd448d1b8fc27dd3501b9bf |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-7d6e5d1f2bd448d1b8fc27dd3501b9bf2025-08-20T02:07:12ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/951910951910Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case ReportXiang-Yan Zhang0Xian-Wei Ye1Duan-Xing Feng2Jing Han3Dan Li4Cheng Zhang5Department of Respiratory Medicine, The People's Hospital of Guizhou Province, No. 83 Zhongshan Dong Road, Guiyang 550002, ChinaDepartment of Respiratory Medicine, The People's Hospital of Guizhou Province, No. 83 Zhongshan Dong Road, Guiyang 550002, ChinaDepartment of Respiratory Medicine, The People's Hospital of Guizhou Province, No. 83 Zhongshan Dong Road, Guiyang 550002, ChinaDepartment of Respiratory Medicine, The People's Hospital of Guizhou Province, No. 83 Zhongshan Dong Road, Guiyang 550002, ChinaDepartment of Respiratory Medicine, The People's Hospital of Guizhou Province, No. 83 Zhongshan Dong Road, Guiyang 550002, ChinaDepartment of Respiratory Medicine, The People's Hospital of Guizhou Province, No. 83 Zhongshan Dong Road, Guiyang 550002, ChinaAfter early outbreaks in North America in April 2009, the pandemic influenza A (H1N1) virus spread rapidly around the world, and even some patients developed certain severe complications. We reported one case of hemophagocytic lymphohistiocytosis (HLH) induced by severe pandemic influenza A (H1N1) virus infection. A 17-year-old girl had acute onset of fever, dry cough, rhinorrhea, and sore throat Her family members and close friends also had the similar symptoms. Anti-infection treatment with penicillin was given after 8 days of the onset of symptoms in the local hospital, and her chest radiograph showed consolidation of the left lung. Then, she was sent to the People's Hospital of Guizhou Province in China and endotracheal intubation were underwent on the ninth day for acute hypoxic respiratory failure. She was diagnosed with HLH induced by severe pandemic influenza A (H1N1) 2009 virus. Oseltamivir, steroids, immunoglobulin, and plasmapheresis were given immediately after admission. After being treated in the People's Hospital of Guizhou Province for 16 days, she was discharged. This experience shows that HLH may be a life-threatening complication for severe pandemic influenza A (H1N1) 2009 virus infection and responds well to therapy.http://dx.doi.org/10.1155/2011/951910 |
| spellingShingle | Xiang-Yan Zhang Xian-Wei Ye Duan-Xing Feng Jing Han Dan Li Cheng Zhang Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report Case Reports in Medicine |
| title | Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report |
| title_full | Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report |
| title_fullStr | Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report |
| title_full_unstemmed | Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report |
| title_short | Hemophagocytic Lymphohistiocytosis Induced by Severe Pandemic Influenza A (H1N1) 2009 Virus Infection: A Case Report |
| title_sort | hemophagocytic lymphohistiocytosis induced by severe pandemic influenza a h1n1 2009 virus infection a case report |
| url | http://dx.doi.org/10.1155/2011/951910 |
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