Distinct Roles Between Eotaxin 1 and Eotaxin 2 in Asthmatic Airways

Distinct Roles Between Eotaxin 1 and Eotaxin 2 in Asthmatic Airways

ABSTRACT Background Eotaxins (EOTs), primarily expressed in airway epithelial cells (AECs), act as chemoattractants for eosinophils in asthma pathogenesis. Recent studies have suggested that EOTs have additional functions beyond chemotaxis. However, the distinct roles of EOTs remain incompletely und...

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Bibliographic Details
Main Authors: Soyoon Sim, Eun‐mi Yang, Yoo Seob Shin, Seon Beom Kim, Youngwoo Choi, Hae‐Sim Park
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Clinical and Translational Allergy
Subjects:
airway epithelial cells
airway remodeling
asthma
eosinophils
eotaxin
neutrophils
Online Access:https://doi.org/10.1002/clt2.70077
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