Roles played by IL-8 in altering dynamics of trabecular meshwork cells after human cytomegalovirus infection

Roles played by IL-8 in altering dynamics of trabecular meshwork cells after human cytomegalovirus infection

Open-angle glaucoma (OAG) is the leading cause of blindness worldwide. Human cytomegalovirus (HCMV) is known to infect the trabecular meshwork cells (HTMCs) and corneal endothelial cells leading to chronic and recurrent elevations of the intraocular pressure (IOP) as secondary glaucoma. To investiga...

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Bibliographic Details
Main Authors: Fumie Ehara, Daisuke Nagase, Masachika Kai, Kaori Adachi, Hitomi Miyake, Yumiko Shimizu, Yoshitsugu Inoue, Dai Miyazaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cytomegalovirus
glaucoma
trabecular meshwork
CXCL8
CCL2
Cdc42
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1550509/full
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