Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report

Bullous pemphigoid is a common subepidermal autoimmune bullous disease that affects the skin and mucous membranes. It is more prevalent in the elderly, often resulting in significant morbidity and mortality. Bullous pemphigoid is rare in solid organ transplant recipients but presents unique challeng...

Full description

Saved in:
Bibliographic Details
Main Authors: Sarah S. Rashid, P. Régine Mydlarski, Fatemeh Jafarian
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251350348
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849422157070729216
author Sarah S. Rashid
P. Régine Mydlarski
Fatemeh Jafarian
author_facet Sarah S. Rashid
P. Régine Mydlarski
Fatemeh Jafarian
author_sort Sarah S. Rashid
collection DOAJ
description Bullous pemphigoid is a common subepidermal autoimmune bullous disease that affects the skin and mucous membranes. It is more prevalent in the elderly, often resulting in significant morbidity and mortality. Bullous pemphigoid is rare in solid organ transplant recipients but presents unique challenges due to their underlying immunosuppression, which increases the risks of infection and adverse drug reactions. Herein, we present the first reported case of dupilumab successfully treating bullous pemphigoid in a liver transplant recipient.
format Article
id doaj-art-7d3bd40f580d43bdb5cd025fb2b7b09a
institution Kabale University
issn 2050-313X
language English
publishDate 2025-06-01
publisher SAGE Publishing
record_format Article
series SAGE Open Medical Case Reports
spelling doaj-art-7d3bd40f580d43bdb5cd025fb2b7b09a2025-08-20T03:31:12ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-06-011310.1177/2050313X251350348Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case reportSarah S. Rashid0P. Régine Mydlarski1Fatemeh Jafarian2Cumming School of Medicine, University of Calgary, AB, CanadaDivision of Dermatology, Department of Medicine, Cumming School of Medicine, University of Calgary, AB, CanadaDivision of Dermatology, Department of Medicine, Cumming School of Medicine, University of Calgary, AB, CanadaBullous pemphigoid is a common subepidermal autoimmune bullous disease that affects the skin and mucous membranes. It is more prevalent in the elderly, often resulting in significant morbidity and mortality. Bullous pemphigoid is rare in solid organ transplant recipients but presents unique challenges due to their underlying immunosuppression, which increases the risks of infection and adverse drug reactions. Herein, we present the first reported case of dupilumab successfully treating bullous pemphigoid in a liver transplant recipient.https://doi.org/10.1177/2050313X251350348
spellingShingle Sarah S. Rashid
P. Régine Mydlarski
Fatemeh Jafarian
Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report
SAGE Open Medical Case Reports
title Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report
title_full Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report
title_fullStr Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report
title_full_unstemmed Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report
title_short Dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient: A case report
title_sort dupilumab as a treatment for bullous pemphigoid in a liver transplant recipient a case report
url https://doi.org/10.1177/2050313X251350348
work_keys_str_mv AT sarahsrashid dupilumabasatreatmentforbullouspemphigoidinalivertransplantrecipientacasereport
AT preginemydlarski dupilumabasatreatmentforbullouspemphigoidinalivertransplantrecipientacasereport
AT fatemehjafarian dupilumabasatreatmentforbullouspemphigoidinalivertransplantrecipientacasereport