Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations.
The article presents the results of a comparative study of the microbial landscape and violations of local immunity in patients with generalized periodontitis at preclinical-radiological stage of development in 60 patients. It was revealed that appearance of representatives of the major periodontal...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2016-12-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/91467 |
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| author | I. S. Mashchenko V. I. Struk N. V. Vatamanyuk |
| author_facet | I. S. Mashchenko V. I. Struk N. V. Vatamanyuk |
| author_sort | I. S. Mashchenko |
| collection | DOAJ |
| description | The article presents the results of a comparative study of the microbial landscape and violations of local immunity in patients with generalized periodontitis at preclinical-radiological stage of development in 60 patients. It was revealed that appearance of representatives of the major periodontal bacteria in the gum tissue is a precursor of development of initial stage of generalized periodontitis in them. It has been established that the early objective indicators of bone resorptive process in periodontal tissues in patients with generalized catarrhal gingivitis is an overproduction of proinflammatory cytokines IL-1.beta and TNF-alpha and the lack of anti-inflammatory IL-4, which persists for a long time during the observation period. |
| format | Article |
| id | doaj-art-7d32d5be3e1d4214a656e57bf720af3b |
| institution | DOAJ |
| issn | 2307-0404 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-7d32d5be3e1d4214a656e57bf720af3b2025-08-20T02:50:48ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042016-12-01214919710.26641/2307-0404.2016.4.9146791467Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations.I. S. MashchenkoV. I. StrukN. V. VatamanyukThe article presents the results of a comparative study of the microbial landscape and violations of local immunity in patients with generalized periodontitis at preclinical-radiological stage of development in 60 patients. It was revealed that appearance of representatives of the major periodontal bacteria in the gum tissue is a precursor of development of initial stage of generalized periodontitis in them. It has been established that the early objective indicators of bone resorptive process in periodontal tissues in patients with generalized catarrhal gingivitis is an overproduction of proinflammatory cytokines IL-1.beta and TNF-alpha and the lack of anti-inflammatory IL-4, which persists for a long time during the observation period.http://journals.uran.ua/index.php/2307-0404/article/view/91467generalized periodontitismicrobiocenosisimmunodeficiency |
| spellingShingle | I. S. Mashchenko V. I. Struk N. V. Vatamanyuk Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations. Medičnì Perspektivi generalized periodontitis microbiocenosis immunodeficiency |
| title | Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations. |
| title_full | Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations. |
| title_fullStr | Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations. |
| title_full_unstemmed | Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations. |
| title_short | Microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre X-ray manifestations. |
| title_sort | microbiological and immunological diagnostic criteria for initial degree of generalized periodontitis at the stage of pre x ray manifestations |
| topic | generalized periodontitis microbiocenosis immunodeficiency |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/91467 |
| work_keys_str_mv | AT ismashchenko microbiologicalandimmunologicaldiagnosticcriteriaforinitialdegreeofgeneralizedperiodontitisatthestageofprexraymanifestations AT vistruk microbiologicalandimmunologicaldiagnosticcriteriaforinitialdegreeofgeneralizedperiodontitisatthestageofprexraymanifestations AT nvvatamanyuk microbiologicalandimmunologicaldiagnosticcriteriaforinitialdegreeofgeneralizedperiodontitisatthestageofprexraymanifestations |