Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008.
<h4>Background</h4>In the context of a rapid increase of dengue cases in the Americas, a monitoring system based on systematic serological control (IgM) of patients consulting for suspected dengue was developed in Bolivia at the end of the 1990s. In the most affected city of Santa Cruz,...
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
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| author | Philippe Brémond Yelin Roca Simone Frédérique Brenière Annie Walter Zaira Barja-Simon Roberto Torres Fernández Jorge Vargas |
| author_facet | Philippe Brémond Yelin Roca Simone Frédérique Brenière Annie Walter Zaira Barja-Simon Roberto Torres Fernández Jorge Vargas |
| author_sort | Philippe Brémond |
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| description | <h4>Background</h4>In the context of a rapid increase of dengue cases in the Americas, a monitoring system based on systematic serological control (IgM) of patients consulting for suspected dengue was developed in Bolivia at the end of the 1990s. In the most affected city of Santa Cruz, this system was complemented by an entomological surveillance program based on periodical search for immature stages of Aedes aegypti in dwelling water-holding containers. Here, we analyze these data and describe dengue patterns over 6 years (2002-2008), highlighting the spatial distribution of patients and vectors.<h4>Methodology /principal findings</h4>Data mining concerned six annual epidemic cycles (2002-2008), with continuous serological and clinical results and entomological data from 16 surveys, examined at the scales of 36 urban areas and four concentric areas covering the entire city. Annual incidence varied from 0.28‰ to 0.95‰; overall incidence was higher in women and adults, and dengue dynamics followed successive periods of high (January-June) and low (July-December) transmission. Lower numbers of cases from the city center to the periphery were observed, poorly related to the more homogeneous and permanent distribution of A. aegypti. "Plant pots" were a major vector source in the city center, and "Tires" and "Odds and ends" beyond the second ring of the city.<h4>Conclusions/significance</h4>Over the years, the increasing trend of dengue cases has been highlighted as well as its widespread distribution over the entire city, but an underestimation of the number of cases is strongly suspected. Contrary to popular belief, the city center appears more affected than the periphery, and dengue is not particularly related to waste. Interestingly, the clinical diagnosis of dengue by physicians improved over the years, whatever the gender, age and residential area of suspected cases. |
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| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-7d32092f50f64268b90e9add096ed4da2025-08-20T02:15:02ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01102e011833710.1371/journal.pone.0118337Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008.Philippe BrémondYelin RocaSimone Frédérique BrenièreAnnie WalterZaira Barja-SimonRoberto Torres FernándezJorge Vargas<h4>Background</h4>In the context of a rapid increase of dengue cases in the Americas, a monitoring system based on systematic serological control (IgM) of patients consulting for suspected dengue was developed in Bolivia at the end of the 1990s. In the most affected city of Santa Cruz, this system was complemented by an entomological surveillance program based on periodical search for immature stages of Aedes aegypti in dwelling water-holding containers. Here, we analyze these data and describe dengue patterns over 6 years (2002-2008), highlighting the spatial distribution of patients and vectors.<h4>Methodology /principal findings</h4>Data mining concerned six annual epidemic cycles (2002-2008), with continuous serological and clinical results and entomological data from 16 surveys, examined at the scales of 36 urban areas and four concentric areas covering the entire city. Annual incidence varied from 0.28‰ to 0.95‰; overall incidence was higher in women and adults, and dengue dynamics followed successive periods of high (January-June) and low (July-December) transmission. Lower numbers of cases from the city center to the periphery were observed, poorly related to the more homogeneous and permanent distribution of A. aegypti. "Plant pots" were a major vector source in the city center, and "Tires" and "Odds and ends" beyond the second ring of the city.<h4>Conclusions/significance</h4>Over the years, the increasing trend of dengue cases has been highlighted as well as its widespread distribution over the entire city, but an underestimation of the number of cases is strongly suspected. Contrary to popular belief, the city center appears more affected than the periphery, and dengue is not particularly related to waste. Interestingly, the clinical diagnosis of dengue by physicians improved over the years, whatever the gender, age and residential area of suspected cases.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118337&type=printable |
| spellingShingle | Philippe Brémond Yelin Roca Simone Frédérique Brenière Annie Walter Zaira Barja-Simon Roberto Torres Fernández Jorge Vargas Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008. PLoS ONE |
| title | Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008. |
| title_full | Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008. |
| title_fullStr | Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008. |
| title_full_unstemmed | Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008. |
| title_short | Evolution of dengue disease and entomological monitoring in Santa Cruz, Bolivia 2002 - 2008. |
| title_sort | evolution of dengue disease and entomological monitoring in santa cruz bolivia 2002 2008 |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118337&type=printable |
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