A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions
The development of local anesthesia in dentistry has marked the beginning of a new era in terms of pain control. Lignocaine is the most commonly used local anesthetic (LA) agent even though it has a vasodilative effect and needs to be combined with adrenaline. Centbucridine is a non-ester, non amide...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2011/795047 |
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| author | Samir Mansuri Ahmed Bhayat Esam Omar Fadi Jarab Mohammad Sami Ahmed |
| author_facet | Samir Mansuri Ahmed Bhayat Esam Omar Fadi Jarab Mohammad Sami Ahmed |
| author_sort | Samir Mansuri |
| collection | DOAJ |
| description | The development of local anesthesia in dentistry has marked the beginning of a new era in terms of pain control. Lignocaine is the most commonly used local anesthetic (LA) agent even though it has a vasodilative effect and needs to be combined with adrenaline. Centbucridine is a non-ester, non amide group LA and has not been comprehensively studied in the dental setting and the objective was to compare it to Lignocaine. This was a randomized study comparing the onset time, duration, depth and cardiovascular parameters between Centbucridine (0.5%) and Lignocaine (2%). The study was conducted in the dental outpatient department at the Government Dental College in India on patients attending for the extraction of lower molars. A total of 198 patients were included and there were no significant differences between the LAs except those who received Centbucridine reported a significantly longer duration of anesthesia compared to those who received Lignocaine. None of the patients reported any side effects. Centbucridine was well tolerated and its substantial duration of anesthesia could be attributed to its chemical compound. Centbucridine can be used for dental procedures and can confidently be used in patients who cannot tolerate Lignocaine or where adrenaline is contraindicated. |
| format | Article |
| id | doaj-art-7d2813117eaf4fdc829b78bd1d01e7ab |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-7d2813117eaf4fdc829b78bd1d01e7ab2025-08-20T03:35:29ZengWileyInternational Journal of Dentistry1687-87281687-87362011-01-01201110.1155/2011/795047795047A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental ExtractionsSamir Mansuri0Ahmed Bhayat1Esam Omar2Fadi Jarab3Mohammad Sami Ahmed4Oral & Maxillofacial Surgery, College of Dentistry, Taibah University, Hizaam Street, P.O. Box 1263, Madinah Munawarah, Saudi ArabiaDental Public Health, College of Dentistry, Taibah University, Hizaam Street, P.O. Box 1263, Madinah Munawarah, Saudi ArabiaOral & Maxillofacial Surgery, College of Dentistry, Taibah University, Hizaam Street, P.O. Box 1263, Madinah Munawarah, Saudi ArabiaOral & Maxillofacial Surgery, College of Dentistry, Taibah University, Hizaam Street, P.O. Box 1263, Madinah Munawarah, Saudi ArabiaDental Public Health, College of Dentistry, Taibah University, Hizaam Street, P.O. Box 1263, Madinah Munawarah, Saudi ArabiaThe development of local anesthesia in dentistry has marked the beginning of a new era in terms of pain control. Lignocaine is the most commonly used local anesthetic (LA) agent even though it has a vasodilative effect and needs to be combined with adrenaline. Centbucridine is a non-ester, non amide group LA and has not been comprehensively studied in the dental setting and the objective was to compare it to Lignocaine. This was a randomized study comparing the onset time, duration, depth and cardiovascular parameters between Centbucridine (0.5%) and Lignocaine (2%). The study was conducted in the dental outpatient department at the Government Dental College in India on patients attending for the extraction of lower molars. A total of 198 patients were included and there were no significant differences between the LAs except those who received Centbucridine reported a significantly longer duration of anesthesia compared to those who received Lignocaine. None of the patients reported any side effects. Centbucridine was well tolerated and its substantial duration of anesthesia could be attributed to its chemical compound. Centbucridine can be used for dental procedures and can confidently be used in patients who cannot tolerate Lignocaine or where adrenaline is contraindicated.http://dx.doi.org/10.1155/2011/795047 |
| spellingShingle | Samir Mansuri Ahmed Bhayat Esam Omar Fadi Jarab Mohammad Sami Ahmed A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions International Journal of Dentistry |
| title | A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions |
| title_full | A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions |
| title_fullStr | A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions |
| title_full_unstemmed | A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions |
| title_short | A Randomized Controlled Trail Comparing the Efficacy of 0.5% Centbucridine to 2% Lignocaine as Local Anesthetics in Dental Extractions |
| title_sort | randomized controlled trail comparing the efficacy of 0 5 centbucridine to 2 lignocaine as local anesthetics in dental extractions |
| url | http://dx.doi.org/10.1155/2011/795047 |
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