Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors

Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors

Abstract Background The gut microbiome represents a novel biomarker for melanoma and non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICI). Gut microbiome metagenomics profiling studies of patients treated with immunotherapy identified bacteria associated with I...

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Main Authors: Khoudia Diop, Babacar Mbaye, Somayeh Nili, Alysé Filin, Myriam Benlaifaoui, Julie Malo, Anne Sophie Renaud, Wiam Belkaid, Sebastian Hunter, Meriem Messaoudene, Karla A. Lee, Arielle Elkrief, Bertrand Routy
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Gut Pathogens
Subjects:
Culturomics
Gut microbiome
Metagenomics sequencing
Lung cancer
Melanoma
Immunotherapy
Online Access:https://doi.org/10.1186/s13099-025-00694-4
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