Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating

High-temperature cooking can induce oxidation and structural changes in myofibrillar protein (MP), harming meat product quality. 6-gingerol is a key part of ginger and a natural antioxidant. In this study, MP was mixed with 6-gingerol and cooked at different temperatures. Chemical methods, fluoresce...

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Main Authors: Ruhong Bai, Anguo Xie, Han Wu, Kun Zhang, Shubei Dong, Yunhong Liu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Foods
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Online Access:https://www.mdpi.com/2304-8158/14/7/1081
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author Ruhong Bai
Anguo Xie
Han Wu
Kun Zhang
Shubei Dong
Yunhong Liu
author_facet Ruhong Bai
Anguo Xie
Han Wu
Kun Zhang
Shubei Dong
Yunhong Liu
author_sort Ruhong Bai
collection DOAJ
description High-temperature cooking can induce oxidation and structural changes in myofibrillar protein (MP), harming meat product quality. 6-gingerol is a key part of ginger and a natural antioxidant. In this study, MP was mixed with 6-gingerol and cooked at different temperatures. Chemical methods, fluorescence spectroscopy, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and molecular docking were used to study the effects on protein aggregation, oxidation, molecular structure, and the microstructure of muscle fibers. The results showed that 40 μg/mL of 6-gingerol significantly optimized the indexes of beef MP. For example, 6-gingerol inhibited the decrease in MP sulfhydryl content and solubility, delayed the rise in surface hydrophobicity and carbonyl content, decreased the particle size of MP, and elevated the absolute value of Zeta potential, which, in turn, hindered oxidative denaturation and the aggregation of proteins. 6-gingerol could maintain the stability of the spatial conformational structure and microstructure of the protein. The protein secondary structure changed, and the α-helical might have been transformed into the β-folded one. The binding of 6-gingerol to MP mainly relied on hydrogen bonds, van der Waals forces, and hydrophobic interactions. Thus, 6-gingerol had a positive effect on the antioxidant properties and structural stability of beef MP during heating.
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spelling doaj-art-7d1bf712a5ef4f4c8e90474ab916d60d2025-08-20T03:06:24ZengMDPI AGFoods2304-81582025-03-01147108110.3390/foods14071081Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During HeatingRuhong Bai0Anguo Xie1Han Wu2Kun Zhang3Shubei Dong4Yunhong Liu5College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, ChinaCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, ChinaZhang Zhongjing School of Chinese Medicine, Nanyang Institute of Technology, Nanyang 473003, ChinaNanyang Biaodian Food Co., Ltd., Nanyang 474250, ChinaCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, ChinaCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, ChinaHigh-temperature cooking can induce oxidation and structural changes in myofibrillar protein (MP), harming meat product quality. 6-gingerol is a key part of ginger and a natural antioxidant. In this study, MP was mixed with 6-gingerol and cooked at different temperatures. Chemical methods, fluorescence spectroscopy, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and molecular docking were used to study the effects on protein aggregation, oxidation, molecular structure, and the microstructure of muscle fibers. The results showed that 40 μg/mL of 6-gingerol significantly optimized the indexes of beef MP. For example, 6-gingerol inhibited the decrease in MP sulfhydryl content and solubility, delayed the rise in surface hydrophobicity and carbonyl content, decreased the particle size of MP, and elevated the absolute value of Zeta potential, which, in turn, hindered oxidative denaturation and the aggregation of proteins. 6-gingerol could maintain the stability of the spatial conformational structure and microstructure of the protein. The protein secondary structure changed, and the α-helical might have been transformed into the β-folded one. The binding of 6-gingerol to MP mainly relied on hydrogen bonds, van der Waals forces, and hydrophobic interactions. Thus, 6-gingerol had a positive effect on the antioxidant properties and structural stability of beef MP during heating.https://www.mdpi.com/2304-8158/14/7/1081beef6-gingeroloxidationmyofibrillar proteintemperatureprotein structure
spellingShingle Ruhong Bai
Anguo Xie
Han Wu
Kun Zhang
Shubei Dong
Yunhong Liu
Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating
Foods
beef
6-gingerol
oxidation
myofibrillar protein
temperature
protein structure
title Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating
title_full Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating
title_fullStr Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating
title_full_unstemmed Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating
title_short Effect of 6-Gingerol on Oxidation and Structure of Beef Myofibrillar Protein During Heating
title_sort effect of 6 gingerol on oxidation and structure of beef myofibrillar protein during heating
topic beef
6-gingerol
oxidation
myofibrillar protein
temperature
protein structure
url https://www.mdpi.com/2304-8158/14/7/1081
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