The mediating effect of depressive syndrome on the relationship between adverse childhood experiences and chronic kidney diseases among middle-aged and older adults

The mediating effect of depressive syndrome on the relationship between adverse childhood experiences and chronic kidney diseases among middle-aged and older adults

BackgroundChronic kidney disease (CKD) is projected to rank among the top five causes of mortality by 2050. In addition to established risk factors, adverse childhood experiences (ACEs) have recently emerged as significant contributors to health risks, including CKD and depressive syndrome (DS). How...

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Bibliographic Details
Main Authors: Xinyao Luo, Ke Wang, Junzhe Ran, Zhuyun Zhang, Yupei Li, Baihai Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Public Health
Subjects:
adverse childhood experiences
chronic kidney disease
depression syndrome
logistic regression
mediation analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1536847/full
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