Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA.

The steroid hormone receptors regulate important physiological functions such as reproduction, metabolism, immunity, and electrolyte balance. Mutations within steroid receptors result in endocrine disorders and can often drive cancer formation and progression. Despite the conserved three-dimensional...

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Bibliographic Details
Main Authors: William H Hudson, Christine Youn, Eric A Ortlund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107000
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