Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA.
The steroid hormone receptors regulate important physiological functions such as reproduction, metabolism, immunity, and electrolyte balance. Mutations within steroid receptors result in endocrine disorders and can often drive cancer formation and progression. Despite the conserved three-dimensional...
Saved in:
| Main Authors: | William H Hudson, Christine Youn, Eric A Ortlund |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0107000 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA.
by: John R Pooley, et al.
Published: (2020-01-01) -
Mineralocorticoid Receptor Blocker Prevents Mineralocorticoid Receptor–Mediated Inflammation by Modulating Transcriptional Activity of Mineralocorticoid Receptor–p65–Signal Transducer and Activator of Transcription 3 Complex
by: Naoto Kuyama, et al.
Published: (2024-09-01) -
Insights into the initiation of JC virus DNA replication derived from the crystal structure of the T-antigen origin binding domain.
by: Gretchen Meinke, et al.
Published: (2014-02-01) -
Mineralocorticoid receptor antagonists reduce inflammatory signaling independent of myofiber mineralocorticoid receptor
by: Jeovanna Lowe, et al.
Published: (2025-12-01) -
Molecular Insights into the Binding of Organophosphate Flame Retardant Key Metabolites with Mineralocorticoid and Estrogen Receptors
by: Syeda Sumayya Tariq, et al.
Published: (2025-05-01)