Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus
Isolated granulomatous noncaseating pancreatitis is a rare condition exceptionally described in human population. We demonstrate a case of the a 71-years-old female patient suffering from recent diabetes mellitus, generalized atherosclerosis and hypertension who died due to pulmonary embolism and te...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2014/615426 |
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| _version_ | 1849409499544158208 |
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| author | Václav Mandys Michal Kheck Michal Anděl |
| author_facet | Václav Mandys Michal Kheck Michal Anděl |
| author_sort | Václav Mandys |
| collection | DOAJ |
| description | Isolated granulomatous noncaseating pancreatitis is a rare condition exceptionally described in human population. We demonstrate a case of the a 71-years-old female patient suffering from recent diabetes mellitus, generalized atherosclerosis and hypertension who died due to pulmonary embolism and terminal bronchopneumonia. Lipomatosis of pancreatic tissue was observed during the postmortem examination. Histological examination of pancreatic tissue discovered multiple small noncaseating epithelioid cell and giant cell granulomas, partly replacing the islets of Langerhans. To our knowledge, our case represents the first description of noninfectious granulomatous pancreatitis associated with acute manifested insulin-dependent diabetes mellitus. |
| format | Article |
| id | doaj-art-7d0a28d9cfc444e3b882b2be9ec14249 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-7d0a28d9cfc444e3b882b2be9ec142492025-08-20T03:35:28ZengWileyCase Reports in Pathology2090-67812090-679X2014-01-01201410.1155/2014/615426615426Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes MellitusVáclav Mandys0Michal Kheck1Michal Anděl2Department of Pathology, Third Faculty of Medicine, Charles University in Prague, 100 00 Prague 10, Czech RepublicDepartment of Pathology, Regional Hospital Jihlava, 586 33 Jihlava, Czech RepublicSecond Department of Internal Medicine, Third Faculty of Medicine, Charles University in Prague, 100 00 Prague, Czech RepublicIsolated granulomatous noncaseating pancreatitis is a rare condition exceptionally described in human population. We demonstrate a case of the a 71-years-old female patient suffering from recent diabetes mellitus, generalized atherosclerosis and hypertension who died due to pulmonary embolism and terminal bronchopneumonia. Lipomatosis of pancreatic tissue was observed during the postmortem examination. Histological examination of pancreatic tissue discovered multiple small noncaseating epithelioid cell and giant cell granulomas, partly replacing the islets of Langerhans. To our knowledge, our case represents the first description of noninfectious granulomatous pancreatitis associated with acute manifested insulin-dependent diabetes mellitus.http://dx.doi.org/10.1155/2014/615426 |
| spellingShingle | Václav Mandys Michal Kheck Michal Anděl Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus Case Reports in Pathology |
| title | Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus |
| title_full | Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus |
| title_fullStr | Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus |
| title_full_unstemmed | Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus |
| title_short | Granulomatous Pancreatitis in a Patient with Acute Manifested Insulin-Dependent Diabetes Mellitus |
| title_sort | granulomatous pancreatitis in a patient with acute manifested insulin dependent diabetes mellitus |
| url | http://dx.doi.org/10.1155/2014/615426 |
| work_keys_str_mv | AT vaclavmandys granulomatouspancreatitisinapatientwithacutemanifestedinsulindependentdiabetesmellitus AT michalkheck granulomatouspancreatitisinapatientwithacutemanifestedinsulindependentdiabetesmellitus AT michalandel granulomatouspancreatitisinapatientwithacutemanifestedinsulindependentdiabetesmellitus |