Protocol for generating human CAR-engineered macrophages by Vpx-containing lentivirus

Summary: Human-derived macrophages are notoriously difficult to infect with HIV-1-based lentiviruses, posing a limitation to the advancement of chimeric antigen receptor macrophage (CAR-M) therapy. Here, we present a protocol for generating human chimeric antigen receptor (CAR)-engineered macrophage...

Full description

Saved in:
Bibliographic Details
Main Authors: Yun Gao, Xiaobin Fang, Luo Zhang, Xiushan Yin
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672400515X
Tags: Add Tag
No Tags, Be the first to tag this record!