Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review

Background. Globally, obesity is becoming a public health problem in the general population. Various determinants were reported by different scholars even though there are inconsistencies. Different biomarkers of obesity were identified for the prediction of obesity. Even though researchers speculat...

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Main Authors: Melese Linger Endalifer, Gedefaw Diress
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2020/6134362
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author Melese Linger Endalifer
Gedefaw Diress
author_facet Melese Linger Endalifer
Gedefaw Diress
author_sort Melese Linger Endalifer
collection DOAJ
description Background. Globally, obesity is becoming a public health problem in the general population. Various determinants were reported by different scholars even though there are inconsistencies. Different biomarkers of obesity were identified for the prediction of obesity. Even though researchers speculate the factors, biomarkers, consequences, and prevention mechanisms, there is a lack of aggregate and purified data in the area of obesity. Summary. In this review, the epidemiology, predisposing factors, biomarkers, consequences, and prevention approaches of obesity were reviewed. Key Messages. The epidemiology of obesity increased in low-, middle-, and high-income countries. Even if the factors vary across regions and socioeconomic levels, sociodemographic, behavioral, and genetic factors were prominent for the development of obesity. There are a lot of biomarkers for obesity, of which microRNA, adipocytes, oxidative stress, blood cell profile, nutrients, and microbiota were promising biomarkers for determination of occurrence of obesity. Since the consequences of obesity are vast and interrelated, multidimensional prevention strategy is mandatory in all nations.
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spelling doaj-art-7cf8dbd882d8470a89630affab7347b02025-08-20T03:35:27ZengWileyJournal of Obesity2090-07082090-07162020-01-01202010.1155/2020/61343626134362Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic ReviewMelese Linger Endalifer0Gedefaw Diress1College of Health Sciences, Woldia University, Woldia, EthiopiaCollege of Health Sciences, Woldia University, Woldia, EthiopiaBackground. Globally, obesity is becoming a public health problem in the general population. Various determinants were reported by different scholars even though there are inconsistencies. Different biomarkers of obesity were identified for the prediction of obesity. Even though researchers speculate the factors, biomarkers, consequences, and prevention mechanisms, there is a lack of aggregate and purified data in the area of obesity. Summary. In this review, the epidemiology, predisposing factors, biomarkers, consequences, and prevention approaches of obesity were reviewed. Key Messages. The epidemiology of obesity increased in low-, middle-, and high-income countries. Even if the factors vary across regions and socioeconomic levels, sociodemographic, behavioral, and genetic factors were prominent for the development of obesity. There are a lot of biomarkers for obesity, of which microRNA, adipocytes, oxidative stress, blood cell profile, nutrients, and microbiota were promising biomarkers for determination of occurrence of obesity. Since the consequences of obesity are vast and interrelated, multidimensional prevention strategy is mandatory in all nations.http://dx.doi.org/10.1155/2020/6134362
spellingShingle Melese Linger Endalifer
Gedefaw Diress
Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review
Journal of Obesity
title Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review
title_full Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review
title_fullStr Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review
title_full_unstemmed Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review
title_short Epidemiology, Predisposing Factors, Biomarkers, and Prevention Mechanism of Obesity: A Systematic Review
title_sort epidemiology predisposing factors biomarkers and prevention mechanism of obesity a systematic review
url http://dx.doi.org/10.1155/2020/6134362
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