Transmission of unfolded protein response—a regulator of disease progression, severity, and spread in virus infections
ABSTRACT The unfolded protein response (UPR) is a cell-autonomous stress response aimed at restoring homeostasis due to the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Viruses often hijack the host cell machinery, leading to an accumulation of misfolded proteins in the ER....
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| Format: | Article |
| Language: | English |
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American Society for Microbiology
2025-02-01
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| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.03522-24 |
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