Tumor-infiltrating lymphocytes in NSCLC: from immune surveillance to immunotherapy

Tumor-infiltrating lymphocytes in NSCLC: from immune surveillance to immunotherapy

Lung cancer, predominantly non-small cell lung cancer (NSCLC), remains a principal driver of cancer-related morbidity and mortality worldwide. Despite advancements in surgery, radiotherapy, chemotherapy, and targeted treatments, outcomes remain poor in advanced NSCLC. The tumor microenvironment (TME...

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Bibliographic Details
Main Authors: Haiyi Xue, Yilan Fan, Yi Li, Qian Zhao, Xuelu Zhang, Pei Zhao, Zhenjun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
lung cancer
tumor microenvironment
immune cells
immunotherapy
CD8 + T cell
B cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1610998/full
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