Novel axial oxygenator with bevelled shape of priming volume
Oxygenators are a lifesaving technology used for blood oxygenation and decarboxylation in case of acute respiratory failure, chronic lung disease, and during open-heart surgery. Devices typically consist of a bundle of thousands of fibre membranes in a housing, with gas flowing inside the fibres and...
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| Format: | Article |
| Language: | English |
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De Gruyter
2024-12-01
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| Series: | Current Directions in Biomedical Engineering |
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| Online Access: | https://doi.org/10.1515/cdbme-2024-2065 |
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| author | Goubergrits Leonid Franke Benedikt |
| author_facet | Goubergrits Leonid Franke Benedikt |
| author_sort | Goubergrits Leonid |
| collection | DOAJ |
| description | Oxygenators are a lifesaving technology used for blood oxygenation and decarboxylation in case of acute respiratory failure, chronic lung disease, and during open-heart surgery. Devices typically consist of a bundle of thousands of fibre membranes in a housing, with gas flowing inside the fibres and blood flowing in the opposite direction outside the fibres. Both ends of the fibre-membranes are fixed with an adhesive to separate gas and blood. The shape of the volume through which the blood flows is determined by the housing of the oxygenator and the internal end surfaces of the fixed ends of the fibre-membrane bundle. The traditional potting process results in a volume shape that is associated with stagnation zones, which are known to promote thrombus formation. In this study, an adapted potting process is proposed which results in a blood compartment with bevelled end faces of the glued bundle parts. Using a numerical study, we have demonstrated that the novel oxygenator design results in optimized flow conditions. |
| format | Article |
| id | doaj-art-7ce765106cd04e008ea049989ff3d88a |
| institution | OA Journals |
| issn | 2364-5504 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj-art-7ce765106cd04e008ea049989ff3d88a2025-08-20T01:47:46ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110426827110.1515/cdbme-2024-2065Novel axial oxygenator with bevelled shape of priming volumeGoubergrits Leonid0Franke Benedikt1Institute of Computer-assisted Cardiovascular Medicine, Deutsches Herzzentrum der Charité, Augustenburger Platz 1, 13353Berlin, GermanyDeutsches Herzzentrum der Charité,Berlin, GermanyOxygenators are a lifesaving technology used for blood oxygenation and decarboxylation in case of acute respiratory failure, chronic lung disease, and during open-heart surgery. Devices typically consist of a bundle of thousands of fibre membranes in a housing, with gas flowing inside the fibres and blood flowing in the opposite direction outside the fibres. Both ends of the fibre-membranes are fixed with an adhesive to separate gas and blood. The shape of the volume through which the blood flows is determined by the housing of the oxygenator and the internal end surfaces of the fixed ends of the fibre-membrane bundle. The traditional potting process results in a volume shape that is associated with stagnation zones, which are known to promote thrombus formation. In this study, an adapted potting process is proposed which results in a blood compartment with bevelled end faces of the glued bundle parts. Using a numerical study, we have demonstrated that the novel oxygenator design results in optimized flow conditions.https://doi.org/10.1515/cdbme-2024-2065oxygenatorpotting processflow designhemodynamics |
| spellingShingle | Goubergrits Leonid Franke Benedikt Novel axial oxygenator with bevelled shape of priming volume Current Directions in Biomedical Engineering oxygenator potting process flow design hemodynamics |
| title | Novel axial oxygenator with bevelled shape of priming volume |
| title_full | Novel axial oxygenator with bevelled shape of priming volume |
| title_fullStr | Novel axial oxygenator with bevelled shape of priming volume |
| title_full_unstemmed | Novel axial oxygenator with bevelled shape of priming volume |
| title_short | Novel axial oxygenator with bevelled shape of priming volume |
| title_sort | novel axial oxygenator with bevelled shape of priming volume |
| topic | oxygenator potting process flow design hemodynamics |
| url | https://doi.org/10.1515/cdbme-2024-2065 |
| work_keys_str_mv | AT goubergritsleonid novelaxialoxygenatorwithbevelledshapeofprimingvolume AT frankebenedikt novelaxialoxygenatorwithbevelledshapeofprimingvolume |