A green approach to the analysis of co-administered ampicillin/sulbactam and paracetamol in human urine

A green approach to the analysis of co-administered ampicillin/sulbactam and paracetamol in human urine

The novelty of this work is the simultaneous analysis of sulbactam (SUL), ampicillin (AMP), and paracetamol (PARA) in human urine samples, using the environmentally benign RP-HPLC method. A C18 column was used in chromatographic separation using potassium dihydrogen phosphate (10 mmol L–1, pH 5)/eth...

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Bibliographic Details
Main Authors: SELIM BASMA M., ABDELSALAM RANDA A., EL-GINDY ALAA, EID BASMA G., NEAMATALLAH THIKRYAT, KHAYYAT AHDAB N., HADAD GHADA M., ELKHOUDARY MAHMOUD M.
Format: Article
Language:English
Published: Sciendo 2022-06-01
Series:Acta Pharmaceutica
Subjects:
ampicillin
paracetamol
sulbactam
hplc
green analytical chemistry
drug-drug interaction
urinary excretion
Online Access:https://doi.org/10.2478/acph-2022-0015
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