Cellular repressor of E1A-stimulated genes 1 enhances skeletal muscle performance through the stimulation of muscle differentiation and Akt-mTOR signaling pathway activation.

Cellular repressor of E1A-stimulated genes 1 enhances skeletal muscle performance through the stimulation of muscle differentiation and Akt-mTOR signaling pathway activation.

Cellular repressor of E1A-stimulated genes 1 (CREG1), a glycoprotein secreted by various cell types, plays a crucial role in cellular differentiation and energy metabolism. While previous research has linked CREG1 deficiency in skeletal muscles to impaired exercise capacity and altered muscle fiber-...

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Bibliographic Details
Main Authors: Ayumi Goto, Michihiro Hashimoto, Sho Yokogawa, Yuzu Naruse, Hitoshi Yamashita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0328485
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