Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results
ABSTRACT Background Most reclassified genetic test results are clinically inactionable and burdensome for healthcare providers to return to patients. The feasibility of using electronic patient portals (e.g., MyChart) to return reclassified results remains unclear. Methods Patient and provider initi...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-07-01
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| Series: | Molecular Genetics & Genomic Medicine |
| Online Access: | https://doi.org/10.1002/mgg3.70123 |
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| _version_ | 1849304197069012992 |
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| author | Sukh Makhnoon MinJae Lee Mujeeb Basit Cindy Kao Sun Won Min Christine Mai Alexa Badalamenti Jacqueline Mersch |
| author_facet | Sukh Makhnoon MinJae Lee Mujeeb Basit Cindy Kao Sun Won Min Christine Mai Alexa Badalamenti Jacqueline Mersch |
| author_sort | Sukh Makhnoon |
| collection | DOAJ |
| description | ABSTRACT Background Most reclassified genetic test results are clinically inactionable and burdensome for healthcare providers to return to patients. The feasibility of using electronic patient portals (e.g., MyChart) to return reclassified results remains unclear. Methods Patient and provider initiated MyChart actions were obtained from MyChart data and matched to patient demographic and clinical information using unique patient medical record numbers. Data on who (patient or provider) sent and read these messages and when (date and time) were collected for clinically actionable and inactionable reclassifications. Results Among 801 patients with 828 reclassified variants in cancer susceptibility genes, 551 had an active MyChart account at the time of reclassification. Patients with active MyChart accounts were less likely to be Hispanic (p < 0.001) compared to other ethnic groups. Of these, 302 (55%) were notified about 308 reclassified results (307 inactionable and 1 actionable) via MyChart messages, and 80% (244/302) read the message within a median time of 3.6 h. Conclusion We find that it is feasible to return reclassified results via electronic patient portals for most patients, but alternative modalities are still necessary. Unidirectional, low‐touch modalities of recontact can be used to efficiently return the increasing number of inactionable reclassified results. |
| format | Article |
| id | doaj-art-7cceb7acd37542dc850b222d5bc83457 |
| institution | Kabale University |
| issn | 2324-9269 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Molecular Genetics & Genomic Medicine |
| spelling | doaj-art-7cceb7acd37542dc850b222d5bc834572025-08-20T03:55:48ZengWileyMolecular Genetics & Genomic Medicine2324-92692025-07-01137n/an/a10.1002/mgg3.70123Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test ResultsSukh Makhnoon0MinJae Lee1Mujeeb Basit2Cindy Kao3Sun Won Min4Christine Mai5Alexa Badalamenti6Jacqueline Mersch7Peter O'donnell School of Public Health University of Texas Southwestern Medical Center Dallas Texas USAPeter O'donnell School of Public Health University of Texas Southwestern Medical Center Dallas Texas USADepartment of Internal Medicine University of Texas Southwestern Dallas Texas USAClinical Informatics Center University of Texas Southwestern Dallas Texas USAClinical Informatics Center University of Texas Southwestern Dallas Texas USAClinical Informatics Center University of Texas Southwestern Dallas Texas USACancer Genetics Program, Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center Dallas Texas USACancer Genetics Program, Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center Dallas Texas USAABSTRACT Background Most reclassified genetic test results are clinically inactionable and burdensome for healthcare providers to return to patients. The feasibility of using electronic patient portals (e.g., MyChart) to return reclassified results remains unclear. Methods Patient and provider initiated MyChart actions were obtained from MyChart data and matched to patient demographic and clinical information using unique patient medical record numbers. Data on who (patient or provider) sent and read these messages and when (date and time) were collected for clinically actionable and inactionable reclassifications. Results Among 801 patients with 828 reclassified variants in cancer susceptibility genes, 551 had an active MyChart account at the time of reclassification. Patients with active MyChart accounts were less likely to be Hispanic (p < 0.001) compared to other ethnic groups. Of these, 302 (55%) were notified about 308 reclassified results (307 inactionable and 1 actionable) via MyChart messages, and 80% (244/302) read the message within a median time of 3.6 h. Conclusion We find that it is feasible to return reclassified results via electronic patient portals for most patients, but alternative modalities are still necessary. Unidirectional, low‐touch modalities of recontact can be used to efficiently return the increasing number of inactionable reclassified results.https://doi.org/10.1002/mgg3.70123 |
| spellingShingle | Sukh Makhnoon MinJae Lee Mujeeb Basit Cindy Kao Sun Won Min Christine Mai Alexa Badalamenti Jacqueline Mersch Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results Molecular Genetics & Genomic Medicine |
| title | Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results |
| title_full | Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results |
| title_fullStr | Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results |
| title_full_unstemmed | Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results |
| title_short | Electronic Patient Portals as a Modality for Returning Reclassified Genetic Test Results |
| title_sort | electronic patient portals as a modality for returning reclassified genetic test results |
| url | https://doi.org/10.1002/mgg3.70123 |
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