Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents
Objective: The at-home bleaching technique leads to the intimate contact of the bleaching gel with gingival tissues, so this study evaluated the immediate inflammatory response, through the edemogenic test, induced by at-home bleaching gels of 10% carbamide peroxide with different desensitizing age...
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| Format: | Article |
| Language: | English |
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Universidade Estadual Paulista
2018-04-01
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| Series: | Brazilian Dental Science |
| Online Access: | https://ojs.ict.unesp.br/index.php/cob/article/view/1526 |
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| author | André Luiz Fraga Briso Marjorie Oliveira Gallinari Francine Benetti Diego Valentim Carlos Roberto Emerenciano Bueno Fabiano Carlos Marson Eloi Dezan Junior Luciano Tavares Ângelo Cintra |
| author_facet | André Luiz Fraga Briso Marjorie Oliveira Gallinari Francine Benetti Diego Valentim Carlos Roberto Emerenciano Bueno Fabiano Carlos Marson Eloi Dezan Junior Luciano Tavares Ângelo Cintra |
| author_sort | André Luiz Fraga Briso |
| collection | DOAJ |
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Objective: The at-home bleaching technique leads to the intimate contact of the bleaching gel with gingival tissues, so this study evaluated the immediate inflammatory response, through the edemogenic test, induced by at-home bleaching gels of 10% carbamide peroxide with different desensitizing agents, the quantification of hydrogen peroxide released and bleaching gels pH. Material and Methods: Forty-eight rats were divided into groups (n=12): CTRL-control group, WP-Whiteness Perfect 10% (FGM Produtos Odontológicos, Joinville, SC, Brazil), OPA-Opalescence 10% (Ultradent Products Inc., South Jordan, IT, USA), and PB-Power Bleaching (BM4, Palhoça, SC, Brazil). For the edemogenic test, all rats received an intravenous injection of Evan's Blue; after 30 min, 0.2 mL of each bleaching gels was injected into the subcutaneous tissue of the rats, and the results of the vascular permeability were assessed after 3 and 6h. The amount of HP released and pH of each product was also determined. Data were submitted to statistical test (p<0.05). Results: At 3h, the PB showed higher vascular permeability than the other groups. At 6h, the PB produced similar vascular permeability than WHI, and higher than OPA and CTRL groups. The OPA group had a higher vascular permeability at 6h compared to 3h; there is no difference in other groups. The PB group had higher HP concentrations than the other groups. Conclusion: In general, the PB caused a more considerable amount of inflammatory edema and higher amount of HP released. This results suggesting that these bleaching gels cause greater aggression in soft gingival tissues that eventually ends up in contact with bleaching products
Keywords
Tooth bleaching; Carbamide peroxide; Hydrogen peroxide; Capillary permeability.
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| format | Article |
| id | doaj-art-7ccc4bd212e1465aa0a396875af9dfda |
| institution | Kabale University |
| issn | 2178-6011 |
| language | English |
| publishDate | 2018-04-01 |
| publisher | Universidade Estadual Paulista |
| record_format | Article |
| series | Brazilian Dental Science |
| spelling | doaj-art-7ccc4bd212e1465aa0a396875af9dfda2025-08-22T19:02:34ZengUniversidade Estadual PaulistaBrazilian Dental Science2178-60112018-04-0121210.14295/bds.2018.v21i2.1526Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agentsAndré Luiz Fraga Briso0Marjorie Oliveira Gallinari1Francine Benetti2Diego Valentim3Carlos Roberto Emerenciano Bueno4Fabiano Carlos Marson5Eloi Dezan Junior6Luciano Tavares Ângelo Cintra7Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.Dental Press Ensino e Pesquisa Ltda – Maringa – PR – Brazil.Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil. Objective: The at-home bleaching technique leads to the intimate contact of the bleaching gel with gingival tissues, so this study evaluated the immediate inflammatory response, through the edemogenic test, induced by at-home bleaching gels of 10% carbamide peroxide with different desensitizing agents, the quantification of hydrogen peroxide released and bleaching gels pH. Material and Methods: Forty-eight rats were divided into groups (n=12): CTRL-control group, WP-Whiteness Perfect 10% (FGM Produtos Odontológicos, Joinville, SC, Brazil), OPA-Opalescence 10% (Ultradent Products Inc., South Jordan, IT, USA), and PB-Power Bleaching (BM4, Palhoça, SC, Brazil). For the edemogenic test, all rats received an intravenous injection of Evan's Blue; after 30 min, 0.2 mL of each bleaching gels was injected into the subcutaneous tissue of the rats, and the results of the vascular permeability were assessed after 3 and 6h. The amount of HP released and pH of each product was also determined. Data were submitted to statistical test (p<0.05). Results: At 3h, the PB showed higher vascular permeability than the other groups. At 6h, the PB produced similar vascular permeability than WHI, and higher than OPA and CTRL groups. The OPA group had a higher vascular permeability at 6h compared to 3h; there is no difference in other groups. The PB group had higher HP concentrations than the other groups. Conclusion: In general, the PB caused a more considerable amount of inflammatory edema and higher amount of HP released. This results suggesting that these bleaching gels cause greater aggression in soft gingival tissues that eventually ends up in contact with bleaching products Keywords Tooth bleaching; Carbamide peroxide; Hydrogen peroxide; Capillary permeability. https://ojs.ict.unesp.br/index.php/cob/article/view/1526 |
| spellingShingle | André Luiz Fraga Briso Marjorie Oliveira Gallinari Francine Benetti Diego Valentim Carlos Roberto Emerenciano Bueno Fabiano Carlos Marson Eloi Dezan Junior Luciano Tavares Ângelo Cintra Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents Brazilian Dental Science |
| title | Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents |
| title_full | Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents |
| title_fullStr | Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents |
| title_full_unstemmed | Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents |
| title_short | Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents |
| title_sort | edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents |
| url | https://ojs.ict.unesp.br/index.php/cob/article/view/1526 |
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