Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review
Plasmablastic lymphoma (PBL) is a rare and aggressive non- Hodgkin 's B-cell lymphoma initially reported in patients with the HIV virus with a predilection for the oral cavity. It can affect individuals with other types of immunodeficiency and appear in extra-oral sites, also demonstrating an a...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024000049 |
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| author | Letícia da Silva Soares Gomes Caroline Alfaia Silva André Luiz Carvalho Barreiros Patrick Rocha Osborne Jeconias Câmara Tiago Novaes Pinheiro Christina Shiang José Augusto Andrade Godoy Bezerra Naíza Menezes Medeiros Abrahim Luciana Botinelly Mendonça Fujimoto |
| author_facet | Letícia da Silva Soares Gomes Caroline Alfaia Silva André Luiz Carvalho Barreiros Patrick Rocha Osborne Jeconias Câmara Tiago Novaes Pinheiro Christina Shiang José Augusto Andrade Godoy Bezerra Naíza Menezes Medeiros Abrahim Luciana Botinelly Mendonça Fujimoto |
| author_sort | Letícia da Silva Soares Gomes |
| collection | DOAJ |
| description | Plasmablastic lymphoma (PBL) is a rare and aggressive non- Hodgkin 's B-cell lymphoma initially reported in patients with the HIV virus with a predilection for the oral cavity. It can affect individuals with other types of immunodeficiency and appear in extra-oral sites, also demonstrating an association with Epstein-Barr Virus (EBV) infection. Histopathological diagnosis is challenging due to overlapping features of other high-grade lymphomas and plasma cell lesions. The objective of the study was to report two cases of oral manifestations of Plasmablastic Lymphoma, in a patient with different HIV serological status and EBV positivity, aiming to present and discuss information regarding the clinical presentation, laboratory and immunohistochemical findings, proposed treatment and a review of updated literature on the topic. |
| format | Article |
| id | doaj-art-7cc6ce1db7a7498ba0290d5200938d8d |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-7cc6ce1db7a7498ba0290d5200938d8d2025-01-09T06:15:10ZengElsevierOral Oncology Reports2772-90602024-03-019100158Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature reviewLetícia da Silva Soares Gomes0Caroline Alfaia Silva1André Luiz Carvalho Barreiros2Patrick Rocha Osborne3Jeconias Câmara4Tiago Novaes Pinheiro5Christina Shiang6José Augusto Andrade Godoy Bezerra7Naíza Menezes Medeiros Abrahim8Luciana Botinelly Mendonça Fujimoto9Department of Pathology and Forensic Medicine, Federal University of Amazonas, Manaus, Amazonas, Brazil; Corresponding author.Department of Pathology and Forensic Medicine, Federal University of Amazonas, Manaus, Amazonas, BrazilDepartment of Health of the Amazon State, Manaus, Amazonas, BrazilFaculty of Dentistry, Federal University of Amazonas, Manaus, Amazonas, BrazilDepartment of Pathology and Forensic Medicine, Federal University of Amazonas, Manaus, Amazonas, BrazilDepartment of Oral Pathology and Oral and Maxillofacial Pathology Service, State University of Amazonas, Manaus, Amazonas, BrazilBacchi Pathology Laboratory, Botucatu, São Paulo, BrazilDepartment of Health of the Amazon State, Manaus, Amazonas, BrazilDepartment of Pathology and Forensic Medicine, Federal University of Amazonas, Manaus, Amazonas, BrazilDepartment of Pathology and Forensic Medicine, Federal University of Amazonas, Manaus, Amazonas, BrazilPlasmablastic lymphoma (PBL) is a rare and aggressive non- Hodgkin 's B-cell lymphoma initially reported in patients with the HIV virus with a predilection for the oral cavity. It can affect individuals with other types of immunodeficiency and appear in extra-oral sites, also demonstrating an association with Epstein-Barr Virus (EBV) infection. Histopathological diagnosis is challenging due to overlapping features of other high-grade lymphomas and plasma cell lesions. The objective of the study was to report two cases of oral manifestations of Plasmablastic Lymphoma, in a patient with different HIV serological status and EBV positivity, aiming to present and discuss information regarding the clinical presentation, laboratory and immunohistochemical findings, proposed treatment and a review of updated literature on the topic.http://www.sciencedirect.com/science/article/pii/S2772906024000049Plasmablastic lymphomaNon-hodgkin lymphomaHIVOral cavityEBV |
| spellingShingle | Letícia da Silva Soares Gomes Caroline Alfaia Silva André Luiz Carvalho Barreiros Patrick Rocha Osborne Jeconias Câmara Tiago Novaes Pinheiro Christina Shiang José Augusto Andrade Godoy Bezerra Naíza Menezes Medeiros Abrahim Luciana Botinelly Mendonça Fujimoto Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review Oral Oncology Reports Plasmablastic lymphoma Non-hodgkin lymphoma HIV Oral cavity EBV |
| title | Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review |
| title_full | Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review |
| title_fullStr | Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review |
| title_full_unstemmed | Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review |
| title_short | Manifestation of plasmablastic lymphoma in the oral cavity: Report of two cases and literature review |
| title_sort | manifestation of plasmablastic lymphoma in the oral cavity report of two cases and literature review |
| topic | Plasmablastic lymphoma Non-hodgkin lymphoma HIV Oral cavity EBV |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024000049 |
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