Unraveling the potential of hypothalamic deep brain stimulation for obesity: Impacts on memory, neuroplasticity and brain metabolism in the Zucker rat

Unraveling the potential of hypothalamic deep brain stimulation for obesity: Impacts on memory, neuroplasticity and brain metabolism in the Zucker rat

Abstract The lateral hypothalamus (LH) plays a key role in regulating energy balance and appetite, making it a potential target for deep brain stimulation (DBS) in treatment-resistant obesity. In this study, we evaluated the short and long-term in vivo effects of continuous LH-DBS over 15 days in a...

Full description

Saved in:
Bibliographic Details
Main Authors: Marta Casquero-Veiga, Meritxell Llorca-Torralba, Clara Bueno-Fernandez, Diego Romero-Miguel, Nicolás Lamanna-Rama, Christine Winter, Esther Berrocoso, Juan Nacher, Manuel Desco, Mª Luisa Soto-Montenegro
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03478-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items