Epigenetic modifications in the murine liver upon depletion of transcriptional coregulator host cell factor 1

Epigenetic modifications in the murine liver upon depletion of transcriptional coregulator host cell factor 1

Abstract Background Transcriptional co-regulators fine-tune gene expression by modulating transcription factor activity and chromatin dynamics. HCF-1 (Host Cell Factor 1), a conserved transcriptional co-regulator, has been implicated in cell cycle progression, liver metabolism, and regeneration. Los...

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Bibliographic Details
Main Authors: Shruti Kaushal, Debashruti Bhattacharya, Saran Kumar, Winship Herr, Jaspreet Kaur Dhanjal, Shilpi Minocha
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Genomics
Subjects:
HCF-1
Epigenetics
Methylation
ChIP-seq
Non-alcoholic fatty liver disease
Online Access:https://doi.org/10.1186/s12864-025-11786-5
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