Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
Peripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal...
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2020-01-01
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Series: | Case Reports in Surgery |
Online Access: | http://dx.doi.org/10.1155/2020/5785413 |
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author | Syed Muhammad Ali Nissar Ahmed Shaikh Zia Aftab Ejaz Latif Muhammad Sameer Muhammad Burhan Khan Mohannad Al-Tarakji |
author_facet | Syed Muhammad Ali Nissar Ahmed Shaikh Zia Aftab Ejaz Latif Muhammad Sameer Muhammad Burhan Khan Mohannad Al-Tarakji |
author_sort | Syed Muhammad Ali |
collection | DOAJ |
description | Peripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal compartment syndrome (ACS) in early course, posterior reversible encephalopathy syndrome (PRES), and splanchnic and extrasplanchnic thrombosis later on. Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. She was diagnosed as having acute biliary pancreatitis and started to be hydrated and was supplemented with analgesia. Her condition deteriorated on the 2nd day, and she was shifted to the surgical intensive care unit (SICU) where she developed abdominal compartment syndrome (ACS), respiratory distress, and acute kidney injury, requiring endotracheal intubation and ventilation. Computerized tomography (CT) showed pancreatic necrosis with multiple fluid collections and significant left-sided pleural effusion. Percutaneous drainage of pleural effusion was done, and she was stabilized to be weaned off from mechanical ventilation. On day 15, she underwent USG-guided drainage of the pancreatic collection and ERCP (endoscopic retrograde cholangiopancreatography) on day 19. Post-ERCP, she had tonic colonic convulsions which were treated with benzodiazepines and phenytoin. It was diagnosed by imaging studies as posterior reversible encephalopathy syndrome (PRES). Her abdomen was still distended and tender; CT showed a significant pseudocyst with splanchnic and extrasplanchnic thrombosis. She had laparotomy, gastrocystostomy, and cholecystectomy on day 28th. She made uncomplicated recovery and discharged in good health. Conclusion. Peripartum pancreatitis can be complicated by ACS, PRES, and splanchnic and extrasplanchnic thrombosis. |
format | Article |
id | doaj-art-7cacb90f6449495b91aa694204b89484 |
institution | Kabale University |
issn | 2090-6900 2090-6919 |
language | English |
publishDate | 2020-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Surgery |
spelling | doaj-art-7cacb90f6449495b91aa694204b894842025-02-03T06:43:38ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/57854135785413Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of LiteratureSyed Muhammad Ali0Nissar Ahmed Shaikh1Zia Aftab2Ejaz Latif3Muhammad Sameer4Muhammad Burhan Khan5Mohannad Al-Tarakji6Department of Acute Care Surgery, Hamad Medical Corporation, Doha, QatarDepartment of Surgical ICU Hamad Medical Corporation, Doha, QatarDepartment of Acute Care Surgery, Hamad Medical Corporation, Doha, QatarDepartment of Acute Care Surgery, Hamad Medical Corporation, Doha, QatarDepartment of Acute Care Surgery, Hamad Medical Corporation, Doha, QatarDepartment of Acute Care Surgery, Hamad Medical Corporation, Doha, QatarDepartment of Acute Care Surgery, Hamad Medical Corporation, Doha, QatarPeripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal compartment syndrome (ACS) in early course, posterior reversible encephalopathy syndrome (PRES), and splanchnic and extrasplanchnic thrombosis later on. Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. She was diagnosed as having acute biliary pancreatitis and started to be hydrated and was supplemented with analgesia. Her condition deteriorated on the 2nd day, and she was shifted to the surgical intensive care unit (SICU) where she developed abdominal compartment syndrome (ACS), respiratory distress, and acute kidney injury, requiring endotracheal intubation and ventilation. Computerized tomography (CT) showed pancreatic necrosis with multiple fluid collections and significant left-sided pleural effusion. Percutaneous drainage of pleural effusion was done, and she was stabilized to be weaned off from mechanical ventilation. On day 15, she underwent USG-guided drainage of the pancreatic collection and ERCP (endoscopic retrograde cholangiopancreatography) on day 19. Post-ERCP, she had tonic colonic convulsions which were treated with benzodiazepines and phenytoin. It was diagnosed by imaging studies as posterior reversible encephalopathy syndrome (PRES). Her abdomen was still distended and tender; CT showed a significant pseudocyst with splanchnic and extrasplanchnic thrombosis. She had laparotomy, gastrocystostomy, and cholecystectomy on day 28th. She made uncomplicated recovery and discharged in good health. Conclusion. Peripartum pancreatitis can be complicated by ACS, PRES, and splanchnic and extrasplanchnic thrombosis.http://dx.doi.org/10.1155/2020/5785413 |
spellingShingle | Syed Muhammad Ali Nissar Ahmed Shaikh Zia Aftab Ejaz Latif Muhammad Sameer Muhammad Burhan Khan Mohannad Al-Tarakji Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature Case Reports in Surgery |
title | Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature |
title_full | Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature |
title_fullStr | Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature |
title_full_unstemmed | Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature |
title_short | Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature |
title_sort | peripartum severe acute pancreatitis with rare complications case report and review of literature |
url | http://dx.doi.org/10.1155/2020/5785413 |
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