Research progress on NLRP3 inflammasome regulation of periodontitis
Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome is a multi-protein complex that exists in the cytoplasm. It is involved in innate immune response and can regulate several inflammatory diseases. Periodontal pathogens can stimulate...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Oral and Maxillofacial Surgery
2024-02-01
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| Series: | Kouqiang hemian waike zazhi |
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| Online Access: | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.01.010 |
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| _version_ | 1849225109945974784 |
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| author | LI Xuejing SU Jiansheng |
| author_facet | LI Xuejing SU Jiansheng |
| author_sort | LI Xuejing |
| collection | DOAJ |
| description | Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome is a multi-protein complex that exists in the cytoplasm. It is involved in innate immune response and can regulate several inflammatory diseases. Periodontal pathogens can stimulate the secretion of several inflammatory cytokines via activating the NLRP3 inflammasome, resulting in periodontal inflammatory disease. This review provides a theoretical overview of periodontal pathogens that are reportedly capable of inflammasome activation, aiming to further exploration of the pathogenesis of chronic periodontitis (CP), which is essential for prevention and developing potential treatment approaches. |
| format | Article |
| id | doaj-art-7ca4bf1bf1244ab099e1db66d100c2ca |
| institution | Kabale University |
| issn | 1005-4979 |
| language | zho |
| publishDate | 2024-02-01 |
| publisher | Editorial Office of Journal of Oral and Maxillofacial Surgery |
| record_format | Article |
| series | Kouqiang hemian waike zazhi |
| spelling | doaj-art-7ca4bf1bf1244ab099e1db66d100c2ca2025-08-25T06:10:50ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-02-01341636610.12439/kqhm.1005-4979.2024.01.010Research progress on NLRP3 inflammasome regulation of periodontitisLI Xuejing0SU Jiansheng1Department of Prosthodontics, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, ChinaDepartment of Prosthodontics, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, ChinaNucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome is a multi-protein complex that exists in the cytoplasm. It is involved in innate immune response and can regulate several inflammatory diseases. Periodontal pathogens can stimulate the secretion of several inflammatory cytokines via activating the NLRP3 inflammasome, resulting in periodontal inflammatory disease. This review provides a theoretical overview of periodontal pathogens that are reportedly capable of inflammasome activation, aiming to further exploration of the pathogenesis of chronic periodontitis (CP), which is essential for prevention and developing potential treatment approaches.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.01.010chronic periodontitisnlrp3 inflammasomeinterleukin-1βred complex |
| spellingShingle | LI Xuejing SU Jiansheng Research progress on NLRP3 inflammasome regulation of periodontitis Kouqiang hemian waike zazhi chronic periodontitis nlrp3 inflammasome interleukin-1β red complex |
| title | Research progress on NLRP3 inflammasome regulation of periodontitis |
| title_full | Research progress on NLRP3 inflammasome regulation of periodontitis |
| title_fullStr | Research progress on NLRP3 inflammasome regulation of periodontitis |
| title_full_unstemmed | Research progress on NLRP3 inflammasome regulation of periodontitis |
| title_short | Research progress on NLRP3 inflammasome regulation of periodontitis |
| title_sort | research progress on nlrp3 inflammasome regulation of periodontitis |
| topic | chronic periodontitis nlrp3 inflammasome interleukin-1β red complex |
| url | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.01.010 |
| work_keys_str_mv | AT lixuejing researchprogressonnlrp3inflammasomeregulationofperiodontitis AT sujiansheng researchprogressonnlrp3inflammasomeregulationofperiodontitis |