Effect of aromatherapy with peppermint, ginger, and lavender on postoperative nausea severity after oral surgery under general anaesthesia: A single-blind randomized controlled trial

Objectives: This study aimed to examine whether aromatherapy with peppermint (Mentha piperita Mitcham), ginger (Zingiber officinale), and lavender (Lavandula angustifolia) reduces the severity of nausea in patients experiencing postoperative nausea after oral surgery under general anaesthesia. Desig...

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Main Authors: Emi Ishikawa, Toshiaki Fujisawa, Yukifumi Kimura, Takayuki Hojo, Nobuhito Kamekura, Kanta Kido
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Complementary Therapies in Medicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S0965229925000445
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Summary:Objectives: This study aimed to examine whether aromatherapy with peppermint (Mentha piperita Mitcham), ginger (Zingiber officinale), and lavender (Lavandula angustifolia) reduces the severity of nausea in patients experiencing postoperative nausea after oral surgery under general anaesthesia. Design: Single-centre, stratified (volatile inhaled anaesthetics used or not and sex, with balanced randomization), single-blind, placebo-controlled study conducted in Japan. Setting: Hokkaido University Hospital. Interventions: Totally, 182 patients were randomized into two groups of aromatherapy: aroma group comprising three essential oils—peppermint, ginger, and lavender—each diluted to 1 % (each dose as pure essential oil was 0.01 ml) and control group with purified water only. Of these, 32 patients in the aroma group and 25 in the control group complained of postoperative nausea and were treated with intervention. Main outcome measures: Change in nausea severity at the onset of postoperative nausea. Results: Nausea severity before the intervention did not differ between groups. Aromatherapy significantly reduced nausea severity (p < 0.001). The percentages of antiemetics used were 30.77 % and 52.38 % in the aroma and control groups, respectively, with no significant difference. The aroma group showed significantly higher satisfaction (p < 0.001). No adverse events were observed during the study. Conclusions: This study indicated that aromatherapy with peppermint, ginger, and lavender significantly improved patient satisfaction and severity of postoperative nausea after oral surgery under general anaesthesia. Therefore, given the benefits of aromatherapy, it would be advantageous to consider a combination of measures that include aromatherapy, as one of the multimodal antiemetic measures.This trial was registered at the Japan Registry of Clinical Trials (jRCTs: 01121002).
ISSN:0965-2299