Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities
Background: Breast density is an independent risk factor for breast cancer and affects the sensitivity of mammography screening. Therefore, new breast imaging approaches could benefit women with increased breast density in early cancer detection and diagnosis. Objectives: To assess the diagnostic pe...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Saudi Journal of Medicine and Medical Sciences |
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| Online Access: | https://journals.lww.com/10.4103/sjmms.sjmms_58_24 |
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| author | Areej S. Aloufi Nuha Khoumais Fayka Ahmed Sara Hosawi Sameera Sulimani Deema Abunayyan Fadiah Alghamdi Samar Alshehri Malak Alsaeed Rasha Sahloul Reem Sabir Elaine F. Harkness Susan M. Astley |
| author_facet | Areej S. Aloufi Nuha Khoumais Fayka Ahmed Sara Hosawi Sameera Sulimani Deema Abunayyan Fadiah Alghamdi Samar Alshehri Malak Alsaeed Rasha Sahloul Reem Sabir Elaine F. Harkness Susan M. Astley |
| author_sort | Areej S. Aloufi |
| collection | DOAJ |
| description | Background:
Breast density is an independent risk factor for breast cancer and affects the sensitivity of mammography screening. Therefore, new breast imaging approaches could benefit women with increased breast density in early cancer detection and diagnosis.
Objectives:
To assess the diagnostic performance of abbreviated breast MRI compared with mammography and other imaging modalities in screening and diagnosing breast cancer among Saudi women with dense breast tissue.
Methods:
A retrospective diagnostic study was conducted using anonymized medical images and histopathology information from 55 women, aged ≥30 years, who had dense breasts (Breast Imaging and Reporting Data System [BI-RADS] breast density categories C and D) and an abnormal mammogram. The sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were calculated for mammography, digital breast tomosynthesis (DBT), synthetic mammography (SM) derived from DBT, ultrasound, and abbreviated breast MRI (ABMRI).
Results:
A total of 19 women had pathology-proven breast cancer. Among all methods, ABMRI showed the highest sensitivity (94.7%) and specificity (58.3%), while mammography showed the lowest (84.2% and 44.4%, respectively). AUC for ABMRI was higher than all the methods including mammography (0.751 vs. 0.643; P < 0.05).
Conclusion:
ABMRI appears to be more accurate in cancer diagnosis than mammography and other modalities for women with dense breast tissue. Further research is advised on a larger sample of Saudi women to confirm the benefit of ABMRI in breast cancer screening and diagnosis for women with increased breast density. |
| format | Article |
| id | doaj-art-7c96aec3d2bc4c478ca1d1e7113d1323 |
| institution | DOAJ |
| issn | 1658-631X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Medicine and Medical Sciences |
| spelling | doaj-art-7c96aec3d2bc4c478ca1d1e7113d13232025-08-20T03:12:41ZengWolters Kluwer Medknow PublicationsSaudi Journal of Medicine and Medical Sciences1658-631X2025-01-0113171710.4103/sjmms.sjmms_58_24Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging ModalitiesAreej S. AloufiNuha KhoumaisFayka AhmedSara HosawiSameera SulimaniDeema AbunayyanFadiah AlghamdiSamar AlshehriMalak AlsaeedRasha SahloulReem SabirElaine F. HarknessSusan M. AstleyBackground: Breast density is an independent risk factor for breast cancer and affects the sensitivity of mammography screening. Therefore, new breast imaging approaches could benefit women with increased breast density in early cancer detection and diagnosis. Objectives: To assess the diagnostic performance of abbreviated breast MRI compared with mammography and other imaging modalities in screening and diagnosing breast cancer among Saudi women with dense breast tissue. Methods: A retrospective diagnostic study was conducted using anonymized medical images and histopathology information from 55 women, aged ≥30 years, who had dense breasts (Breast Imaging and Reporting Data System [BI-RADS] breast density categories C and D) and an abnormal mammogram. The sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were calculated for mammography, digital breast tomosynthesis (DBT), synthetic mammography (SM) derived from DBT, ultrasound, and abbreviated breast MRI (ABMRI). Results: A total of 19 women had pathology-proven breast cancer. Among all methods, ABMRI showed the highest sensitivity (94.7%) and specificity (58.3%), while mammography showed the lowest (84.2% and 44.4%, respectively). AUC for ABMRI was higher than all the methods including mammography (0.751 vs. 0.643; P < 0.05). Conclusion: ABMRI appears to be more accurate in cancer diagnosis than mammography and other modalities for women with dense breast tissue. Further research is advised on a larger sample of Saudi women to confirm the benefit of ABMRI in breast cancer screening and diagnosis for women with increased breast density.https://journals.lww.com/10.4103/sjmms.sjmms_58_24abbreviated breast mribreast cancerbreast densitydiagnostic accuracymammographysaudi arabia |
| spellingShingle | Areej S. Aloufi Nuha Khoumais Fayka Ahmed Sara Hosawi Sameera Sulimani Deema Abunayyan Fadiah Alghamdi Samar Alshehri Malak Alsaeed Rasha Sahloul Reem Sabir Elaine F. Harkness Susan M. Astley Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities Saudi Journal of Medicine and Medical Sciences abbreviated breast mri breast cancer breast density diagnostic accuracy mammography saudi arabia |
| title | Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities |
| title_full | Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities |
| title_fullStr | Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities |
| title_full_unstemmed | Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities |
| title_short | Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities |
| title_sort | accuracy of abbreviated breast mri in diagnosing breast cancer in women with dense breasts compared with standard imaging modalities |
| topic | abbreviated breast mri breast cancer breast density diagnostic accuracy mammography saudi arabia |
| url | https://journals.lww.com/10.4103/sjmms.sjmms_58_24 |
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