Development of a reliable risk prognostic model for lung adenocarcinoma based on the genes related to endotheliocyte senescence

Abstract Cellular senescence is a hallmark for cancers, particularly in lung adenocarcinoma (LUAD). This study developed a risk model using senescence signature genes for LUAD patients. Based on the RNA-seq, clinical information and mutation data of LUAD patients collected from the TCGA and GEO data...

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Bibliographic Details
Main Authors: Hongzhi Li, Guangming Li, Xian Gao, Chengde Chen, Zhongfeng Cui, Xiaojiu Cao, Jing Su
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-95551-4
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