Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial

Abstract Background To evaluate the clinical efficacy and outcomes of C-Root SP bioceramic-based sealers combined with different obturation techniques in nonsurgical root canal treatment for older patients. Methods This prospective, single-center, single-blind, parallel, randomized clinical trial in...

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Main Authors: Liping Dong, Jianshe Li, Peng Xue, Suixin Hu, Chen Xu, Lin Wang, Liu Liu, Qiang Luo, Huixia He, Fei Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Oral Health
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Online Access:https://doi.org/10.1186/s12903-025-06117-9
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author Liping Dong
Jianshe Li
Peng Xue
Suixin Hu
Chen Xu
Lin Wang
Liu Liu
Qiang Luo
Huixia He
Fei Chen
author_facet Liping Dong
Jianshe Li
Peng Xue
Suixin Hu
Chen Xu
Lin Wang
Liu Liu
Qiang Luo
Huixia He
Fei Chen
author_sort Liping Dong
collection DOAJ
description Abstract Background To evaluate the clinical efficacy and outcomes of C-Root SP bioceramic-based sealers combined with different obturation techniques in nonsurgical root canal treatment for older patients. Methods This prospective, single-center, single-blind, parallel, randomized clinical trial included 240 patients aged ≥ 60 years. Patients were randomly divided into four treatment groups. Group A: C-Root SP combined with single-cone (SC); Group B: C-Root SP combined with warm vertical compaction (WVC); Group C: C-Root SP combined with cold lateral condensation (CLC); Group D: iRoot SP combined with SC (Control). All teeth were subjected to root canal filling using the corresponding methods 7–10 days after root canal preparation and medication. The duration of obturation was recorded. Periapical radiographs were obtained immediately after obturation to determine the length of root canal filling, and postoperative pain on days 1, 2, and 7 was documented. The treatment outcomes based on clinical signs and symptoms as well as periapical index (PAI) were analyzed at 1 year postoperatively. Results Groups A and D exhibited significantly higher filling efficiency than groups B and C (P < 0.001). No significant differences were observed in the length of obturation between the groups (P > 0.05). Postoperative pain decreased over time in all groups, with group A showing significantly lower pain rates on day 1 than the other groups (P < 0.05). After 1 year, all groups exhibited considerable reductions in the PAI scores, with success rates ranging from 91.23 to 94.83%; however, no significant differences were observed between them (P > 0.05). Conclusions C-Root SP combined with different obturation techniques yielded similar outcomes to iRoot SP combined with the SC technique in terms of filling length, success rate, and changes in PAI scores. The SC technique demonstrated significant advantages in terms of clinical efficiency and may reduce early postoperative pain when combined with C-Root SP. Trial registration The study was retrospectively registered in chictr.org.cn with the identifier: ChiCTR2400092580 on 11/19/2024.
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spelling doaj-art-7c8bd7c761aa4ad0b67c54ec48b1ff472025-08-20T01:51:28ZengBMCBMC Oral Health1472-68312025-05-0125111510.1186/s12903-025-06117-9Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trialLiping Dong0Jianshe Li1Peng Xue2Suixin Hu3Chen Xu4Lin Wang5Liu Liu6Qiang Luo7Huixia He8Fei Chen9Department of Stomatology, The First Medical Center, Chinese PLA General HospitalOutpatient Department of TPL, Southern Medical Branch of PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalDepartment of Stomatology, The First Medical Center, Chinese PLA General HospitalAbstract Background To evaluate the clinical efficacy and outcomes of C-Root SP bioceramic-based sealers combined with different obturation techniques in nonsurgical root canal treatment for older patients. Methods This prospective, single-center, single-blind, parallel, randomized clinical trial included 240 patients aged ≥ 60 years. Patients were randomly divided into four treatment groups. Group A: C-Root SP combined with single-cone (SC); Group B: C-Root SP combined with warm vertical compaction (WVC); Group C: C-Root SP combined with cold lateral condensation (CLC); Group D: iRoot SP combined with SC (Control). All teeth were subjected to root canal filling using the corresponding methods 7–10 days after root canal preparation and medication. The duration of obturation was recorded. Periapical radiographs were obtained immediately after obturation to determine the length of root canal filling, and postoperative pain on days 1, 2, and 7 was documented. The treatment outcomes based on clinical signs and symptoms as well as periapical index (PAI) were analyzed at 1 year postoperatively. Results Groups A and D exhibited significantly higher filling efficiency than groups B and C (P < 0.001). No significant differences were observed in the length of obturation between the groups (P > 0.05). Postoperative pain decreased over time in all groups, with group A showing significantly lower pain rates on day 1 than the other groups (P < 0.05). After 1 year, all groups exhibited considerable reductions in the PAI scores, with success rates ranging from 91.23 to 94.83%; however, no significant differences were observed between them (P > 0.05). Conclusions C-Root SP combined with different obturation techniques yielded similar outcomes to iRoot SP combined with the SC technique in terms of filling length, success rate, and changes in PAI scores. The SC technique demonstrated significant advantages in terms of clinical efficiency and may reduce early postoperative pain when combined with C-Root SP. Trial registration The study was retrospectively registered in chictr.org.cn with the identifier: ChiCTR2400092580 on 11/19/2024.https://doi.org/10.1186/s12903-025-06117-9Bioceramic-based sealersClinical trialEndodontic outcomesObturation techniquePostoperative pain
spellingShingle Liping Dong
Jianshe Li
Peng Xue
Suixin Hu
Chen Xu
Lin Wang
Liu Liu
Qiang Luo
Huixia He
Fei Chen
Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial
BMC Oral Health
Bioceramic-based sealers
Clinical trial
Endodontic outcomes
Obturation technique
Postoperative pain
title Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial
title_full Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial
title_fullStr Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial
title_full_unstemmed Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial
title_short Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial
title_sort clinical outcomes of nonsurgical root canal treatment using c root sp combined with different obturation techniques in older patients a randomized controlled clinical trial
topic Bioceramic-based sealers
Clinical trial
Endodontic outcomes
Obturation technique
Postoperative pain
url https://doi.org/10.1186/s12903-025-06117-9
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