Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration

Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration

Abstract Epigenetic regulation of neuronal transcriptomic landscape is emerging to be a key coordinator of mammalian neural regeneration. The roles of two histone 3 lysine 27 (H3K27) demethylases, Kdm6a/b, in controlling neuroprotection and axon regeneration are investigated here. Deleting either Kd...

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Main Authors: Shu‐Guang Yang, Chang‐Ping Li, Xue‐Wei Wang, Tao Huang, Cheng Qian, Qiao Li, Ling‐Rui Zhao, Si‐Yu Zhou, Chen‐Yun Ding, Rui Nie, Saijilafu, Yu‐Cai Hong, Chang‐Mei Liu, Feng‐Quan Zhou
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
epigenetic regulation
histone methylation
Kdm6a
Kdm6b
Klf4
neuroprotection
Online Access:https://doi.org/10.1002/advs.202405537
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