Research advances of histone deacetylases in acute kidney injury

Histone deacetylases (HDACs) are expressed by silencing the deacetylation of histone lysine.HDACs can also deacetylate non-histone proteins and regulate cell biological functions.Abnormal function of HDACs is closely correlated with the occurrence and development of tumor,neurodegenerative disease,i...

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Bibliographic Details
Main Authors: Deng Fang-jing, Zhu Jie-fu, Wu Xiong-fei
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2022-04-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.04.012
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Summary:Histone deacetylases (HDACs) are expressed by silencing the deacetylation of histone lysine.HDACs can also deacetylate non-histone proteins and regulate cell biological functions.Abnormal function of HDACs is closely correlated with the occurrence and development of tumor,neurodegenerative disease,inflammatory reactive disease and kidney disease.This review summarized the latest researches of HDACs in acute kidney injury.
ISSN:1671-2390