Findings of optical coherence tomography angiography of nasal optic disc hypoplasia

Purpose: This study aimed to present a case of a woman diagnosed with congenital nasal optic disc hypoplasia (NOH) in the right eye. Observations: A woman in her 20s presented with a small optic disc, irregular optic disc margins with a double-ring sign, and wedge-shaped defects temporally extending...

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Main Authors: Miki Yoshimura, Yuki Hashimoto, Arisu Hatanaka, Takeshi Yoshitomi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:American Journal of Ophthalmology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2451993624002081
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author Miki Yoshimura
Yuki Hashimoto
Arisu Hatanaka
Takeshi Yoshitomi
author_facet Miki Yoshimura
Yuki Hashimoto
Arisu Hatanaka
Takeshi Yoshitomi
author_sort Miki Yoshimura
collection DOAJ
description Purpose: This study aimed to present a case of a woman diagnosed with congenital nasal optic disc hypoplasia (NOH) in the right eye. Observations: A woman in her 20s presented with a small optic disc, irregular optic disc margins with a double-ring sign, and wedge-shaped defects temporally extending from Mariotte's blind spot in the right eye. The radial peripapillary capillary (RPC) density around the optic nerve disc was examined using optical coherence tomography angiography (OCTA). The best-corrected visual acuity was 1.2 OU, and intraocular pressure was 12 mmHg OU. Optical coherence tomography C-scan detected thinning of the circumpapillary retinal nerve fiber layer, and OCTA revealed that a decrease in RPC density on the nasal side of the optic disc in the right eye was markedly lower than that in the other eye areas. Furthermore, it was lower than the RPC density on the nasal side of the left eye. Conclusions and importance: OCTA may help detect the clinical features and pathogenesis of NOH.
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publishDate 2024-12-01
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spelling doaj-art-7c4f1e97f32a4b2aa9b9909e039aed972025-08-20T02:48:58ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362024-12-013610219810.1016/j.ajoc.2024.102198Findings of optical coherence tomography angiography of nasal optic disc hypoplasiaMiki Yoshimura0Yuki Hashimoto1Arisu Hatanaka2Takeshi Yoshitomi3Department of Orthoptics, Faculty of Medicine, Fukuoka International University of Health and Welfare, Fukuoka, JapanCorresponding author. Department of Orthoptics, Faculty of Medicine, Fukuoka International University of Health and Welfare, Momochihama 3-6-40, Sawara-ku, Fukuoka, 814-0001, Japan.; Department of Orthoptics, Faculty of Medicine, Fukuoka International University of Health and Welfare, Fukuoka, JapanDepartment of Orthoptics, Faculty of Medicine, Fukuoka International University of Health and Welfare, Fukuoka, JapanDepartment of Orthoptics, Faculty of Medicine, Fukuoka International University of Health and Welfare, Fukuoka, JapanPurpose: This study aimed to present a case of a woman diagnosed with congenital nasal optic disc hypoplasia (NOH) in the right eye. Observations: A woman in her 20s presented with a small optic disc, irregular optic disc margins with a double-ring sign, and wedge-shaped defects temporally extending from Mariotte's blind spot in the right eye. The radial peripapillary capillary (RPC) density around the optic nerve disc was examined using optical coherence tomography angiography (OCTA). The best-corrected visual acuity was 1.2 OU, and intraocular pressure was 12 mmHg OU. Optical coherence tomography C-scan detected thinning of the circumpapillary retinal nerve fiber layer, and OCTA revealed that a decrease in RPC density on the nasal side of the optic disc in the right eye was markedly lower than that in the other eye areas. Furthermore, it was lower than the RPC density on the nasal side of the left eye. Conclusions and importance: OCTA may help detect the clinical features and pathogenesis of NOH.http://www.sciencedirect.com/science/article/pii/S2451993624002081Circumpapillary retinal nerve fiber layerNasal optic disc hypoplasiaOptical coherence tomography angiographyRadial peripapillary capillary
spellingShingle Miki Yoshimura
Yuki Hashimoto
Arisu Hatanaka
Takeshi Yoshitomi
Findings of optical coherence tomography angiography of nasal optic disc hypoplasia
American Journal of Ophthalmology Case Reports
Circumpapillary retinal nerve fiber layer
Nasal optic disc hypoplasia
Optical coherence tomography angiography
Radial peripapillary capillary
title Findings of optical coherence tomography angiography of nasal optic disc hypoplasia
title_full Findings of optical coherence tomography angiography of nasal optic disc hypoplasia
title_fullStr Findings of optical coherence tomography angiography of nasal optic disc hypoplasia
title_full_unstemmed Findings of optical coherence tomography angiography of nasal optic disc hypoplasia
title_short Findings of optical coherence tomography angiography of nasal optic disc hypoplasia
title_sort findings of optical coherence tomography angiography of nasal optic disc hypoplasia
topic Circumpapillary retinal nerve fiber layer
Nasal optic disc hypoplasia
Optical coherence tomography angiography
Radial peripapillary capillary
url http://www.sciencedirect.com/science/article/pii/S2451993624002081
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AT arisuhatanaka findingsofopticalcoherencetomographyangiographyofnasalopticdischypoplasia
AT takeshiyoshitomi findingsofopticalcoherencetomographyangiographyofnasalopticdischypoplasia