Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis

Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis

ABSTRACT Multiple sclerosis (MS) is an autoimmune disease causing neuroinflammation and demyelination in the central nervous system (CNS). It is traditionally considered CD4+ T cell‐mediated, but several immune cells, such as CD8+ cells, B cells, macrophages, and dendritic cells (DC) also contribute...

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Main Authors: Ana Isabel Álvarez‐López, Eduardo Ponce‐España, Ivan Cruz‐Chamorro, Guillermo Santos‐Sánchez, Ignacio Bejarano, Nuria Álvarez‐Sánchez, Patricia Judith Lardone, Antonio Carrillo‐Vico
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:MedComm
Subjects:
C57BL/6J
C57BL/6N
multiple sclerosis
microbiota
mouse model
neuroinflammation
Online Access:https://doi.org/10.1002/mco2.70228
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