Clinical and Genomic Landscape of FGFR3 Alterations Across Different Stages of Urothelial Cancer

Clinical and Genomic Landscape of FGFR3 Alterations Across Different Stages of Urothelial Cancer

Background and objective: Our aim was to provide a comprehensive analysis of the prevalence of potentially targetable activating FGFR3 alterations and their impact on oncological outcomes across different urothelial carcinoma (UC) stages. Methods: We retrospectively analyzed clinical data and FGFR3...

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Main Authors: Maximilian Haas, Roman Mayr, Danijel Sikic, Bernd Wullich, Niklas Klümper, Philipp Erben, Ralph Wirtz, Christian Bolenz, Florian Roghmann, Robert Stöhr, Veronika Bahlinger, Arndt Hartmann, Maximilian Burger, Johannes Breyer, Markus Eckstein
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:European Urology Open Science
Subjects:
FGFR3 alteration
Targeted therapy
Urothelial carcinoma
Proliferation
Tumor growth
Online Access:http://www.sciencedirect.com/science/article/pii/S2666168325001181
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