Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants

Purpose. To evaluate the repeatability of measurement of central corneal thickness (CCT) by spectral domain optical coherence (SD-OCT) in premature infants and compare it to CCT measurement by ultrasonic pachymetry (USP). Methods. Three CCT measurements of the left eyes of 50 premature infants were...

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Main Authors: Emre Hekimoglu, Muhammet Kazım Erol, Devrim Toslak, Deniz Turgut Coban, Berna Doğan, Ozgur Yucel
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/129269
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author Emre Hekimoglu
Muhammet Kazım Erol
Devrim Toslak
Deniz Turgut Coban
Berna Doğan
Ozgur Yucel
author_facet Emre Hekimoglu
Muhammet Kazım Erol
Devrim Toslak
Deniz Turgut Coban
Berna Doğan
Ozgur Yucel
author_sort Emre Hekimoglu
collection DOAJ
description Purpose. To evaluate the repeatability of measurement of central corneal thickness (CCT) by spectral domain optical coherence (SD-OCT) in premature infants and compare it to CCT measurement by ultrasonic pachymetry (USP). Methods. Three CCT measurements of the left eyes of 50 premature infants were obtained by SD-OCT using the iVue system. 10 CCT measurements of each 28 left eyes of 28 infants were obtained by USP using the Pacscan 300P system. Bland-Altman plots were developed and the limit of agreement (LoA) was determined to compare the mean of the SD-OCT and USP measurements. Results. No statistically significant difference was found among the 3 CCT measurements by SD-OCT. Both USP and SD-OCT have been performed for only left eyes of 28 of the 50 babies. Those results have been compared with each other. A statistically significant difference was found between the mean CCT measurements by SD-OCT and USP (p<0.05). The LoA between the SD-OCT and USP measurements ranged from 11.4 to −64.1. Conclusions. CCT can be measured using the iVue SD-OCT system with a high level of repeatability. Although measurement of CCT by SD-OCT and USP is highly correlated, the 2 systems cannot be used interchangeably in premature infants.
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institution Kabale University
issn 2090-004X
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language English
publishDate 2015-01-01
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series Journal of Ophthalmology
spelling doaj-art-7c43d69ee72542b0b510fe5b9bef8f3b2025-02-03T00:59:20ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/129269129269Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature InfantsEmre Hekimoglu0Muhammet Kazım Erol1Devrim Toslak2Deniz Turgut Coban3Berna Doğan4Ozgur Yucel5Ophthalmology Department, Etlik Zubeyde Hanim Maternity and Women’s Health Research Hospital, Yeni Etlik Caddesi No:55, Etlik, Keçiören, 06010 Ankara, TurkeyOphthalmology Department, Antalya Training and Research Hospital, Varlık Mah., Kazım Karabekir Caddesi, Muratpaşa, 07100 Antalya, TurkeyOphthalmology Department, Antalya Training and Research Hospital, Varlık Mah., Kazım Karabekir Caddesi, Muratpaşa, 07100 Antalya, TurkeyOphthalmology Department, Antalya Training and Research Hospital, Varlık Mah., Kazım Karabekir Caddesi, Muratpaşa, 07100 Antalya, TurkeyOphthalmology Department, Antalya Training and Research Hospital, Varlık Mah., Kazım Karabekir Caddesi, Muratpaşa, 07100 Antalya, TurkeyOphthalmology Department, Antalya Training and Research Hospital, Varlık Mah., Kazım Karabekir Caddesi, Muratpaşa, 07100 Antalya, TurkeyPurpose. To evaluate the repeatability of measurement of central corneal thickness (CCT) by spectral domain optical coherence (SD-OCT) in premature infants and compare it to CCT measurement by ultrasonic pachymetry (USP). Methods. Three CCT measurements of the left eyes of 50 premature infants were obtained by SD-OCT using the iVue system. 10 CCT measurements of each 28 left eyes of 28 infants were obtained by USP using the Pacscan 300P system. Bland-Altman plots were developed and the limit of agreement (LoA) was determined to compare the mean of the SD-OCT and USP measurements. Results. No statistically significant difference was found among the 3 CCT measurements by SD-OCT. Both USP and SD-OCT have been performed for only left eyes of 28 of the 50 babies. Those results have been compared with each other. A statistically significant difference was found between the mean CCT measurements by SD-OCT and USP (p<0.05). The LoA between the SD-OCT and USP measurements ranged from 11.4 to −64.1. Conclusions. CCT can be measured using the iVue SD-OCT system with a high level of repeatability. Although measurement of CCT by SD-OCT and USP is highly correlated, the 2 systems cannot be used interchangeably in premature infants.http://dx.doi.org/10.1155/2015/129269
spellingShingle Emre Hekimoglu
Muhammet Kazım Erol
Devrim Toslak
Deniz Turgut Coban
Berna Doğan
Ozgur Yucel
Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants
Journal of Ophthalmology
title Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants
title_full Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants
title_fullStr Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants
title_full_unstemmed Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants
title_short Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature Infants
title_sort comparison of measurement of central corneal thickness with spectral domain optical coherence tomography and standard ultrasonic pachymeter in premature infants
url http://dx.doi.org/10.1155/2015/129269
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