RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets
A reverse phase HPLC method is developed for the determination of Raloxifene in pharmaceutical dosage forms. Chromatography was carried out on an inertsil C18 column using a mixture of acetonitrile and phosphate buffer (30:70 v/v) as the mobile phase at a flow rate of 1 mL/min. Detection was carried...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2006/713569 |
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| _version_ | 1849408562792497152 |
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| author | P. Venkata Reddy B. Sudha Rani G. Srinu Babu J. V. L. N. Seshagiri Rao |
| author_facet | P. Venkata Reddy B. Sudha Rani G. Srinu Babu J. V. L. N. Seshagiri Rao |
| author_sort | P. Venkata Reddy |
| collection | DOAJ |
| description | A reverse phase HPLC method is developed for the determination of Raloxifene in pharmaceutical dosage forms. Chromatography was carried out on an inertsil C18 column using a mixture of acetonitrile and phosphate buffer (30:70 v/v) as the mobile phase at a flow rate of 1 mL/min. Detection was carried out at 290 nm .The retention time of the drug was 10.609 min. The method produced linear responses in the concentration range of 0.5-200 µg/mL of Raloxifene. The method was found to be applicable for determination of the drug in tablets. |
| format | Article |
| id | doaj-art-7c40fd8d1acd422d9b02bfe45aa447bd |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-7c40fd8d1acd422d9b02bfe45aa447bd2025-08-20T03:35:45ZengWileyE-Journal of Chemistry0973-49452090-98102006-01-0131606410.1155/2006/713569RP-HPLC Determination of Raloxifene in Pharmaceuticl TabletsP. Venkata Reddy0B. Sudha Rani1G. Srinu Babu2J. V. L. N. Seshagiri Rao3College of Pharmaceutical Sciences, Andhra University., Visakhapatnam-530003, IndiaCollege of Pharmaceutical Sciences, Andhra University., Visakhapatnam-530003, IndiaCollege of Pharmaceutical Sciences, Andhra University., Visakhapatnam-530003, IndiaCollege of Pharmaceutical Sciences, Andhra University., Visakhapatnam-530003, IndiaA reverse phase HPLC method is developed for the determination of Raloxifene in pharmaceutical dosage forms. Chromatography was carried out on an inertsil C18 column using a mixture of acetonitrile and phosphate buffer (30:70 v/v) as the mobile phase at a flow rate of 1 mL/min. Detection was carried out at 290 nm .The retention time of the drug was 10.609 min. The method produced linear responses in the concentration range of 0.5-200 µg/mL of Raloxifene. The method was found to be applicable for determination of the drug in tablets.http://dx.doi.org/10.1155/2006/713569 |
| spellingShingle | P. Venkata Reddy B. Sudha Rani G. Srinu Babu J. V. L. N. Seshagiri Rao RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets E-Journal of Chemistry |
| title | RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets |
| title_full | RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets |
| title_fullStr | RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets |
| title_full_unstemmed | RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets |
| title_short | RP-HPLC Determination of Raloxifene in Pharmaceuticl Tablets |
| title_sort | rp hplc determination of raloxifene in pharmaceuticl tablets |
| url | http://dx.doi.org/10.1155/2006/713569 |
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