A role for astrocytic miR-129-5p in frontotemporal dementia

A role for astrocytic miR-129-5p in frontotemporal dementia

Abstract Frontotemporal dementia is a debilitating neurodegenerative disorder characterized by frontal and temporal lobe degeneration, resulting in behavioral changes, language difficulties, and cognitive decline. In this study, smallRNA sequencing was conducted on postmortem brain tissues obtained...

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Main Authors: Lalit Kaurani, Ranjit Pradhan, Sophie Schröder, Susanne Burkhardt, Anna-Lena Schuetz, Dennis M. Krüger, Tonatiuh Pena, Peter Heutink, Farahnaz Sananbenesi, Andre Fischer
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03338-y
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