Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review

Abstract Background Integrating phytomedicine with glass ionomer cements (GICs) offers a promising avenue for improving dental restoratives. This review comprehensively discusses the incorporation of plant extracts and derivatives into GICs to enhance their antimicrobial, mechanical, and aesthetic p...

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Main Authors: Dina Ezzat, Amr Azab, Ibrahim S. Kamel, Mohamed Abdelmonem, Mohamed Ahmed Ibrahim, Abdullah Ayad, Romesa Soomro, Mohamed Wagdy, Mohamed Eldebawy
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Online Access:https://doi.org/10.1186/s43088-025-00633-x
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author Dina Ezzat
Amr Azab
Ibrahim S. Kamel
Mohamed Abdelmonem
Mohamed Ahmed Ibrahim
Abdullah Ayad
Romesa Soomro
Mohamed Wagdy
Mohamed Eldebawy
author_facet Dina Ezzat
Amr Azab
Ibrahim S. Kamel
Mohamed Abdelmonem
Mohamed Ahmed Ibrahim
Abdullah Ayad
Romesa Soomro
Mohamed Wagdy
Mohamed Eldebawy
author_sort Dina Ezzat
collection DOAJ
description Abstract Background Integrating phytomedicine with glass ionomer cements (GICs) offers a promising avenue for improving dental restoratives. This review comprehensively discusses the incorporation of plant extracts and derivatives into GICs to enhance their antimicrobial, mechanical, and aesthetic properties. Main text The addition of plant extracts, such as propolis, miswak, and grape seed, and the respective disinfecting derivatives of gallic acid, epigallocatechin-3-gallate, and curcumin improved both the antibacterial and mechanical properties of GICs. Furthermore, the incorporation of these derivatives is in line with current practices, which emphasize the use of natural products to minimize the use of synthetic preservatives in dental applications. In addition, this review discussed the role of these plant extracts in the green synthesis of nanoparticles (NPs), providing insights into how these sustainable approaches can fill existing gaps in dental material technology. This intersection of plant-based compounds and nanotechnology not only paves the way for innovative dental materials but also supports the broader movement toward sustainable practices in dentistry. This review revealed that the incorporation of plant extracts may significantly improve the antimicrobial properties of GICs and maintain or slightly improve their mechanical properties; however, the disparate methodologies and extraction concentrations used in these studies call for further standardized research. Conclusion This review highlights the potential of phytomedicine to optimize the performance of GICs in clinical settings and calls for further research to establish the most effective formulations.
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spelling doaj-art-7c3138cb3cd44c35b8a373cd6e6084f62025-08-20T02:25:13ZengSpringerOpenBeni-Suef University Journal of Basic and Applied Sciences2314-85432025-05-0114112210.1186/s43088-025-00633-xPhytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive reviewDina Ezzat0Amr Azab1Ibrahim S. Kamel2Mohamed Abdelmonem3Mohamed Ahmed Ibrahim4Abdullah Ayad5Romesa Soomro6Mohamed Wagdy7Mohamed Eldebawy8Tanta UniversityTanta UniversityPort Said UniversityUniversiti Putra MalaysiaUniversiti Putra MalaysiaUniversity of BasrahUniversiti Putra MalaysiaModern University for Information and TechnologyTanta UniversityAbstract Background Integrating phytomedicine with glass ionomer cements (GICs) offers a promising avenue for improving dental restoratives. This review comprehensively discusses the incorporation of plant extracts and derivatives into GICs to enhance their antimicrobial, mechanical, and aesthetic properties. Main text The addition of plant extracts, such as propolis, miswak, and grape seed, and the respective disinfecting derivatives of gallic acid, epigallocatechin-3-gallate, and curcumin improved both the antibacterial and mechanical properties of GICs. Furthermore, the incorporation of these derivatives is in line with current practices, which emphasize the use of natural products to minimize the use of synthetic preservatives in dental applications. In addition, this review discussed the role of these plant extracts in the green synthesis of nanoparticles (NPs), providing insights into how these sustainable approaches can fill existing gaps in dental material technology. This intersection of plant-based compounds and nanotechnology not only paves the way for innovative dental materials but also supports the broader movement toward sustainable practices in dentistry. This review revealed that the incorporation of plant extracts may significantly improve the antimicrobial properties of GICs and maintain or slightly improve their mechanical properties; however, the disparate methodologies and extraction concentrations used in these studies call for further standardized research. Conclusion This review highlights the potential of phytomedicine to optimize the performance of GICs in clinical settings and calls for further research to establish the most effective formulations.https://doi.org/10.1186/s43088-025-00633-xGlass ionomer cementPhytomedicinePlant extractsAntimicrobial propertiesMechanical propertiesDentistry
spellingShingle Dina Ezzat
Amr Azab
Ibrahim S. Kamel
Mohamed Abdelmonem
Mohamed Ahmed Ibrahim
Abdullah Ayad
Romesa Soomro
Mohamed Wagdy
Mohamed Eldebawy
Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review
Beni-Suef University Journal of Basic and Applied Sciences
Glass ionomer cement
Phytomedicine
Plant extracts
Antimicrobial properties
Mechanical properties
Dentistry
title Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review
title_full Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review
title_fullStr Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review
title_full_unstemmed Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review
title_short Phytomedicine and green nanotechnology: enhancing glass ionomer cements for sustainable dental restorations: a comprehensive review
title_sort phytomedicine and green nanotechnology enhancing glass ionomer cements for sustainable dental restorations a comprehensive review
topic Glass ionomer cement
Phytomedicine
Plant extracts
Antimicrobial properties
Mechanical properties
Dentistry
url https://doi.org/10.1186/s43088-025-00633-x
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