Effects of Cd on brain AChE and metabolic enzymes in tissues of T. Nilotics

T. Nilotics was exposed to two water environments which contained 0.5 mg/L Cd and 5.0 mg/L Cd, respectively, for about 28 days. The brain acetylcholinesterase (AChE) and the lactic dehydrogenase (LDH), alanine aminotransferase (ALT) and aspartic transaminase (AST) in gill, liver and heart were assay...

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Bibliographic Details
Main Authors: HUI Tian-chao, WANG Jia-gang, ZHU Ying-mei, CHENG Xiao-ming, LU Yong-gan
Format: Article
Language:English
Published: Zhejiang University Press 2004-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2004.06.0673
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Summary:T. Nilotics was exposed to two water environments which contained 0.5 mg/L Cd and 5.0 mg/L Cd, respectively, for about 28 days. The brain acetylcholinesterase (AChE) and the lactic dehydrogenase (LDH), alanine aminotransferase (ALT) and aspartic transaminase (AST) in gill, liver and heart were assayed. The result shows that both high dose of Cd and low dose of Cd pollution for a long time led to inhibition of AChE. LDH activity in the three organs significantly decreased in the high dose Cd group, the sequence of degree of decrease being liver > heart > gill. On the other hand, in the low Cd group, the LDH activity significantly rose at the late stage. ALT and AST remarkable decreased in both Cd groups, the levels of ALT activity in organs being liver > heart > gill and of AST heart > liver >gill. It is concluded that higher dose of Cd may disturb nervous functions of T. Nilotics and gly-cometabolism process. In addition, Cd can damage bistiocyte and is more harmful to hepatic cell then to heart and gill cell.
ISSN:1008-9209
2097-5155