Forsythiaside A Reduces Acetaminophen Hepatotoxic Metabolism by Inhibiting Pregnane X Receptor

Forsythiaside A Reduces Acetaminophen Hepatotoxic Metabolism by Inhibiting Pregnane X Receptor

Overdose intake of acetaminophen (APAP) causes liver injury involving hepatic drug metabolism and activation of oxidative stress pathways, and forsythiaside A (FA) has hepatoprotective pharmacological activity, but knowledge of the mechanism of FA treatment for APAP liver injury is still lacking the...

Full description

Saved in:
Bibliographic Details
Main Authors: Sisi Pu, Yangyang Pan, Zuoyang Wang, Huimin Liu, Jianhui Zhang, Qian Zhang, Meng Wang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
forsythiaside A
pregnane X receptor
acetaminophen metabolism
oxidative stress
endoplasmic reticulum stress
apoptosis
Online Access:https://www.mdpi.com/1420-3049/30/5/1187
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items