The impact of tacrolimus levels on acute GVHD and transplant outcomes in haploidentical hematopoietic stem cell transplantation: A retrospective analysis

The impact of tacrolimus levels on acute GVHD and transplant outcomes in haploidentical hematopoietic stem cell transplantation: A retrospective analysis

The impact of early tacrolimus (TAC) blood levels on acute graft-versus-host disease (aGVHD) and transplant outcomes in adults undergoing haploidentical hematopoietic stem cell transplantation (haplo-HSCT) with posttransplant cyclophosphamide (PTCy) is incompletely investigated. We retrospectively a...

Full description

Saved in:

Bibliographic Details
Main Authors:	Alexander Nikoloudis, Veronika Buxhofer-Ausch, Ameya Kunte, Christina Groiss, Lorenz Mair, Christoph Aichinger, Michaela Binder, Petra Hasengruber, Emine Kaynak, Dagmar Wipplinger, Robert Milanov, Irene Strassl, Olga Stiefel, Sigrid Machherndl-Spandl, Holger Rumpold, Ansgar Weltermann, Andreas Petzer, Johannes Clausen
Format:	Article
Language:	English
Published:	SAGE Publishing 2025-08-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.1177/09636897251366368
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Post-transplant cyclophosphamide in haploidentical stem cell transplantation: evaluating the impact of transplant conditioning intensity
by: Umberto Pizzano, et al.
Published: (2025-08-01)

Haploidentical Stem Cell Transplantation With Dual Source of Cells and Post‐Transplant Cyclophosphamide
by: Ana Marcela Rojas Fonseca‐Hial, et al.
Published: (2025-02-01)

Post-transplant cyclophosphamide or cell selection in haploidentical allogeneic hematopoietic cell transplantation?
by: Razan Mohty, et al.
Published: (2024-12-01)

Haploidentical Transplantation in Children with Acute Leukemia: The Unresolved Issues
by: Sarita Rani Jaiswal, et al.
Published: (2016-01-01)

Future directions in haploidentical hematopoietic stem cell transplantation
by: Pongthep Vittayawacharin, et al.
Published: (2024-12-01)

IMMUNITY TO INFECTIONS AFTER HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION
by: Franco Aversa, et al.
Published: (2016-10-01)

Current status of conditioning regimens in haploidentical hematopoietic cell transplantation
by: Junichi Sugita, et al.
Published: (2024-12-01)

Haploidentical Hematopoietic Stem Cell Transplantation: Expanding the Horizon for Hematologic Disorders
by: Mohammad Faizan Zahid, et al.
Published: (2016-01-01)

Natural Killer (NK) Cell Alloreactivity in Haploidentical Stem Cell Transplantation
by: Mar Luis-Hidalgo, et al.
Published: (2025-07-01)

HLA and Non-HLA Factors for Donor Selection in Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide GvHD Prophylaxis
by: Hiroko Shike, et al.
Published: (2024-12-01)

Haploidentical, matched-related, and matched-unrelated hematopoietic cell transplant for acute leukemias in the early years of haploidentical transplant implementation in a developing country with a large unrelated donor registry
by: Adriana Seber, et al.
Published: (2025-04-01)

Letermovir prophylaxis for cytomegalovirus is associated with risk of post-transplant lymphoproliferative disorders after haploidentical stem cell transplantation
by: Xu-Ying Pei, et al.
Published: (2024-11-01)

Intermediate-dose posttransplantation cyclophosphamide for myeloablative HLA-haploidentical bone marrow transplantation
by: Mustafa A. Hyder, et al.
Published: (2025-05-01)

COMPARISON OF INFECTIOUS COMPLICATIONS IN PATIENTS RECEIVING HIGH-DOSE CYCLOPHOSPHAMIDE AS GVHD AFTER TRANSPLANTATION FROM A 9/10 HLA-MATCHED UNRELATED DONOR WITH STANDARD GVHD PROPHYLAXIS AFTER TRANSPLANT FROM A FULL MATCHING DONOR
by: Selim SAYIN
Published: (2024-02-01)

Donor‐derived M2 macrophages attenuate GVHD after allogeneic hematopoietic stem cell transplantation
by: Ryo Hanaki, et al.
Published: (2021-12-01)

Myeloablative Conditioning with PBSC Grafts for T Cell-Replete Haploidentical Donor Transplantation Using Posttransplant Cyclophosphamide
by: Scott R. Solomon, et al.
Published: (2016-01-01)

Immune Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Different Non‐T‐Cell Depletion Protocols
by: Xiao‐Di Ma, et al.
Published: (2025-06-01)

Optimizing Haploidentical Hematopoietic Stem Cell Transplantation: Enhancing Outcomes in Hematologic Malignancies in Resource-Limited Settings
by: Owattanapanich W, et al.
Published: (2025-03-01)

Allogeneic hematopoietic stem cell transplantation for thalassemia major using matched unrelated donors and haploidentical related donors
by: Feiyan Wang, et al.
Published: (2025-02-01)

A Case of Myeloproliferative Neoplasm with BCR-FGFR1 Rearrangement: Favorable Outcome after Haploidentical Allogeneic Transplantation
by: Paola Villafuerte-Gutiérrez, et al.
Published: (2018-01-01)

The use of haploidentical stem cell transplant as an alternative donor source in patients with decreased access to matched unrelated donors
by: Christopher Graham, et al.
Published: (2024-12-01)

A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
by: Dan Han, et al.
Published: (2021-01-01)

Sirolimus-Based Immunosuppression as GvHD Prophylaxis after Bone Marrow Transplantation for Severe Aplastic Anaemia: A Case Report and Review of the Literature
by: Katia Perruccio, et al.
Published: (2015-01-01)

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model
by: Shinri Sato, et al.
Published: (2025-01-01)

How to reduce the risk of primary engraftment failure after haploidentical hematopoietic stem cell transplantation in patients with acute myeloid leukemia?
by: D. K. Zhogolev, et al.
Published: (2025-03-01)

Prediction and effect on relapse of natural killer cell alloreactivity based on KIR-HLA interactions in pediatric haploidentical transplantation with anti-thymoglobulin
by: Xiang-Feng Tang, et al.
Published: (2025-08-01)

Hemorrhagic cystitis in pediatric severe aplastic anemia undergoing haploidentical hematopoietic stem cell transplantation: incidence, risk factors and outcomes
by: Kai Cui, et al.
Published: (2025-03-01)

Double Infection in a Patient with Chronic GVHD Post Allogeneic Transplant: “Hickam's Dictum” Trumps “Occam's Razor”!—A Case Report with Review of Literature
by: Fen Saj, et al.

Triple stem cell infusion alleviated graft-versus-host disease and improves outcomes in unmanipulated haploidentical hematopoietic stem cell transplantation
by: Fang Hua, et al.
Published: (2025-07-01)

Haploidentical Allogeneic Stem Cell Transplantation as a Superior Alternative for Patients With Mismatch Donors—A Single Center Experience in 152 Patients
by: Paul Jäger, et al.
Published: (2025-04-01)

Impact of post-transplant cyclophosphamide with bendamustine on immune reconstitution in young patients undergoing T-cell replete haploidentical bone marrow transplantation: results from a phase Ia/Ib clinical trial
by: Forrest L. Baker, et al.
Published: (2025-04-01)

HLA typing and STR loci chimerism analysis of a case of acute lymphoblastic leukemia after HLA haploidentical hematopoietic stem cell transplantation
by: QUAN Zhanrou, et al.
Published: (2025-07-01)

Intrathecal tocilizumab for immune-mediated central nervous system complication after haploidentical hematopoietic stem cell transplantation in children: Two case reports
by: Ruirui Gui, et al.
Published: (2024-11-01)

Infectious Complications after Haploidentical Hematopoietic Stem Cells Transplantation in Patients with High-Risk Tumors of Hematopoietic and Lymphoid Tissues: A Single-Center Experience
by: YuS Osipov, et al.
Published: (2019-09-01)

Risk factors and clinical outcomes of cytomegalovirus infection following haploidentical hematopoietic stem cell transplantation in patients with aplastic anemia: a single-center retrospective study
by: Jia Feng, et al.
Published: (2025-01-01)

MIF functional polymorphisms are associated with acute GVHD progression and steroid-refractoriness
by: Aviran Aharon, et al.
Published: (2025-04-01)

Orthotopic Liver Transplantation: Is There a Risk for Listeria monocytogenes Infection?
by: Urs Ehehalt, et al.
Published: (2010-01-01)

The rationale behind grafting haploidentical hematopoietic stem cells
by: Richard T. Maziarz, et al.
Published: (2024-12-01)

Reduced morbidity and mortality of cGVHD in patients who received treatment with mesenchymal stromal cells for steroid-resistant aGVHD: long-term follow-up of a randomized phase 3 trial
by: Ke Zhao, et al.
Published: (2025-07-01)

Posttransplant cyclophosphamide as GVHD prophylaxis in patients receiving mismatched unrelated HCT: the PHYLOS trial
by: Anna Maria Raiola, et al.
Published: (2025-04-01)