Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria
Background: Exfoliated nasal mucosa cells were studied among morticians exposed to formaldehyde in Benin City, Nigeria. Materials and Methods: 50 subjects were divided into five groups A,B,C,D and E according to their duration (in years) of exposure with 10 subjects in each group. Group A served...
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Nigerian Medical Association, Akwa Ibom State Branch
2025-04-01
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| Series: | Ibom Medical Journal |
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| Online Access: | http://ibommedicaljournal.org/index.php/imjhome/article/view/664 |
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| author | Ebojele FO Aihie EO |
| author_facet | Ebojele FO Aihie EO |
| author_sort | Ebojele FO |
| collection | DOAJ |
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Background: Exfoliated nasal mucosa cells were studied among morticians exposed to formaldehyde in Benin City, Nigeria.
Materials and Methods: 50 subjects were divided into five groups A,B,C,D and E according to their duration (in years) of exposure with 10 subjects in each group. Group A served as control with nil exposure while groups B,C,D and E served as the test groups with 0-5 years, 6-10 years, 11-20 years, and > 20years exposures respectively. Anthropometric parameters of subjects were measured and cytology of exfoliated nasal epithelia cells was done. Statistical analysis was done using GraphPad prism version 5.0 and p<0.05 was considered as statistically significant.
Results: Results showed infiltration of chronic inflammatory cells and progressive increase in nuclear-cytoplasmic ratio (N-C ratio) with exposure duration.
Conclusion: It was therefore concluded that exposure to formaldehyde for a prolonged period could have cytotoxic effect on the respiratory tract among morticians.
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| format | Article |
| id | doaj-art-7c21e21df8a644baa5dc8ae87855b0f2 |
| institution | DOAJ |
| issn | 1597-7188 2735-9964 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nigerian Medical Association, Akwa Ibom State Branch |
| record_format | Article |
| series | Ibom Medical Journal |
| spelling | doaj-art-7c21e21df8a644baa5dc8ae87855b0f22025-08-20T02:39:16ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642025-04-0118210.61386/imj.v18i2.664Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, NigeriaEbojele FO0Aihie EO1Department of Physiology, School of Basic Medical Sciences, College of Medical Sciences, University of Benin, Benin City, NigeriaDepartment of Physiology, School of Basic Medical Sciences, College of Medical Sciences, University of Benin, Benin City, Nigeria. Background: Exfoliated nasal mucosa cells were studied among morticians exposed to formaldehyde in Benin City, Nigeria. Materials and Methods: 50 subjects were divided into five groups A,B,C,D and E according to their duration (in years) of exposure with 10 subjects in each group. Group A served as control with nil exposure while groups B,C,D and E served as the test groups with 0-5 years, 6-10 years, 11-20 years, and > 20years exposures respectively. Anthropometric parameters of subjects were measured and cytology of exfoliated nasal epithelia cells was done. Statistical analysis was done using GraphPad prism version 5.0 and p<0.05 was considered as statistically significant. Results: Results showed infiltration of chronic inflammatory cells and progressive increase in nuclear-cytoplasmic ratio (N-C ratio) with exposure duration. Conclusion: It was therefore concluded that exposure to formaldehyde for a prolonged period could have cytotoxic effect on the respiratory tract among morticians. http://ibommedicaljournal.org/index.php/imjhome/article/view/664formaldehydecytologynasal mucosaexfoliatedmorticians |
| spellingShingle | Ebojele FO Aihie EO Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria Ibom Medical Journal formaldehyde cytology nasal mucosa exfoliated morticians |
| title | Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria |
| title_full | Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria |
| title_fullStr | Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria |
| title_full_unstemmed | Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria |
| title_short | Assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in Benin City, Nigeria |
| title_sort | assessment of exfoliated nasal mucosa cells among morticians exposed to formaldehyde in benin city nigeria |
| topic | formaldehyde cytology nasal mucosa exfoliated morticians |
| url | http://ibommedicaljournal.org/index.php/imjhome/article/view/664 |
| work_keys_str_mv | AT ebojelefo assessmentofexfoliatednasalmucosacellsamongmorticiansexposedtoformaldehydeinbenincitynigeria AT aihieeo assessmentofexfoliatednasalmucosacellsamongmorticiansexposedtoformaldehydeinbenincitynigeria |